Naloxone binding in the frontal cortex of postmortem human brain
Küçük Resim Yok
Tarih
1989
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
1. The binding of 3H-Naloxone to opiate receptors was characterized in the frontal cortex of human post-mortem brain samples and age related changes in opiate receptors were investigated. 2. Our study revealed the presence of two binding sites with different affinities for naloxone. 3. With increasing age, the opiate receptors tend to show greater affinity for the agonistic conformation; this may imply a decline in endogenous opioid peptides with age. © 1989.
Açıklama
Anahtar Kelimeler
Aging, naloxone, opiate receptor, post-mortem human brain
Kaynak
Progress in Neuropsychopharmacology and Biological Psychiatry
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
13
Sayı
01.Feb
