Stevens-Johnson syndrome associated with methotrexate treatment for acute lymphoblastic leukemia: a case report

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dc.contributor.authorAkinci, Burcu
dc.contributor.authorSivis, Zuhal O.
dc.contributor.authorSahin, Akkiz
dc.contributor.authorKarapinar, Deniz Y.
dc.contributor.authorBalkan, Can
dc.contributor.authorKavakli, Kaan
dc.contributor.authorAydinok, Yesim
dc.date.accessioned2019-10-27T10:04:56Z
dc.date.available2019-10-27T10:04:56Z
dc.date.issued2018
dc.departmentEge Üniversitesien_US
dc.description.abstractToxic epidermal necrolysis and Stevens-Johnson syndrome are rare mucocutaneous diseases which are associated with a prolonged course and potentially lethal outcome. They are mostly drug induced and mortality rates are very high. Although mostly skin is involved, multiple organ systems such as cardiovascular, pulmonary, gastrointestinal, and urinary systems may be affected. Here, we report a case of Stevens-Johnson Syndrome associated with methotrexate treatment who developed acute cardiac failure and gastrointestinal hemorrhage beside skin findings. He had been treated with intravenous immunglobulin and methylprednisolone succesfully and continued chemotherapy with methotrexate treatment again.en_US
dc.identifier.doi10.5546/aap.2018.eng.e459en_US
dc.identifier.endpageE462en_US
dc.identifier.issn0325-0075
dc.identifier.issn1668-3501
dc.identifier.issue3en_US
dc.identifier.pmid29756724en_US
dc.identifier.startpageE459en_US
dc.identifier.urihttps://doi.org/10.5546/aap.2018.eng.e459
dc.identifier.urihttps://hdl.handle.net/11454/30299
dc.identifier.volume116en_US
dc.identifier.wosWOS:000434010200026en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSoc Argentina Pediatriaen_US
dc.relation.ispartofArchivos Argentinos De Pediatriaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectStevens-Johnson syndromeen_US
dc.subjecttoxic epidermal necrolysisen_US
dc.subjectmethotrexateen_US
dc.subjectleukemiaen_US
dc.subjectchilden_US
dc.titleStevens-Johnson syndrome associated with methotrexate treatment for acute lymphoblastic leukemia: a case reporten_US
dc.typeArticleen_US

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