Stevens-Johnson syndrome associated with methotrexate treatment for acute lymphoblastic leukemia: a case report

Küçük Resim Yok

Tarih

2018

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Soc Argentina Pediatria

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Toxic epidermal necrolysis and Stevens-Johnson syndrome are rare mucocutaneous diseases which are associated with a prolonged course and potentially lethal outcome. They are mostly drug induced and mortality rates are very high. Although mostly skin is involved, multiple organ systems such as cardiovascular, pulmonary, gastrointestinal, and urinary systems may be affected. Here, we report a case of Stevens-Johnson Syndrome associated with methotrexate treatment who developed acute cardiac failure and gastrointestinal hemorrhage beside skin findings. He had been treated with intravenous immunglobulin and methylprednisolone succesfully and continued chemotherapy with methotrexate treatment again.

Açıklama

Anahtar Kelimeler

Stevens-Johnson syndrome, toxic epidermal necrolysis, methotrexate, leukemia, child

Kaynak

Archivos Argentinos De Pediatria

WoS Q Değeri

Q4

Scopus Q Değeri

Cilt

116

Sayı

3

Künye