Stevens-Johnson syndrome associated with methotrexate treatment for acute lymphoblastic leukemia: a case report
Küçük Resim Yok
Tarih
2018
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Soc Argentina Pediatria
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Toxic epidermal necrolysis and Stevens-Johnson syndrome are rare mucocutaneous diseases which are associated with a prolonged course and potentially lethal outcome. They are mostly drug induced and mortality rates are very high. Although mostly skin is involved, multiple organ systems such as cardiovascular, pulmonary, gastrointestinal, and urinary systems may be affected. Here, we report a case of Stevens-Johnson Syndrome associated with methotrexate treatment who developed acute cardiac failure and gastrointestinal hemorrhage beside skin findings. He had been treated with intravenous immunglobulin and methylprednisolone succesfully and continued chemotherapy with methotrexate treatment again.
Açıklama
Anahtar Kelimeler
Stevens-Johnson syndrome, toxic epidermal necrolysis, methotrexate, leukemia, child
Kaynak
Archivos Argentinos De Pediatria
WoS Q Değeri
Q4
Scopus Q Değeri
Cilt
116
Sayı
3