Biological and physical properties of calcium hydroxide-based pulp-capping materials and their modifications

dc.authoridARMAGAN, GULIZ/0000-0001-6466-2263
dc.authoridAtes, Mustafa/0000-0001-7449-5454
dc.authoridakin, dilek/0000-0003-1713-7508
dc.authoridAtes, Mustafa/0000-0002-8871-5638
dc.authoridBirim, Dervis/0000-0002-5094-9949
dc.authoridATALAYIN OZKAYA, Cigdem/0000-0003-4144-4233
dc.contributor.authorAkin, Dilek
dc.contributor.authorOzkaya, Cigdem Atalayin
dc.contributor.authorArmagan, Guliz
dc.contributor.authorBirim, Dervis
dc.contributor.authorAtes, Mustafa
dc.contributor.authorTezel, Huseyin
dc.date.accessioned2024-08-31T07:47:06Z
dc.date.available2024-08-31T07:47:06Z
dc.date.issued2024
dc.departmentEge Üniversitesien_US
dc.description.abstractPurpose: To evaluate the biological and physical properties of calcium hydroxide -containing pulp -capping materials and their modifications with different solutions and antioxidant Resveratrol (RES) addition. Methods: Calcium hydroxide+distilled-water:C, calcium hydroxide+saline:S, calcium hydroxide+synthetic tissue fluid:STF, Dycal:D, calcium hydroxide+distilled-water+RES:C+RES, calcium hydroxide+saline+RES:S+RES, calcium hydroxide+synthetic tissue fluid+RES:STF+RES, Dycal+RES:D+RES were tested. Cytotoxicity was determined by WST-1. Antibacterial -activity was evaluated by agar -diffusion. The water -absorption and solubility were examined for ISO -6876 and ISO -3107. The color -change was evaluated by spectrophotometer. Radiopacity was evaluated for ISO -6876 and ISO -9917. The normal distribution and homogeneity were determined and comparisons were made with appropriate analysis and post hoc tests (P < 0.05). Results: The highest cell -viability was determined in the C+RES and the lowest was in D and D+RES after 24 h (P < 0.0001). RES-addition increased cell -viability and the highest rate was detected in C+RES, S+RES and STF+RES after 48 h (P < 0.0001). A limited inhibition -zone against Streptococcus mutans was detected in D and D+RES. RES-addition did not change the water -absorption in S and STF or the solubility in S group. Conclusion: RES-addition may be used to increase the biocompatibility of calcium hydroxide without any adverse effect on physical properties. Saline may be the first choice as a mixing solution.en_US
dc.identifier.doi10.2334/josnusd.23-0288
dc.identifier.endpage95en_US
dc.identifier.issn1343-4934
dc.identifier.issn1880-4926
dc.identifier.issue2en_US
dc.identifier.pmid38325856en_US
dc.identifier.scopus2-s2.0-85190904077en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage91en_US
dc.identifier.urihttps://doi.org/10.2334/josnusd.23-0288
dc.identifier.urihttps://hdl.handle.net/11454/104309
dc.identifier.volume66en_US
dc.identifier.wosWOS:001207587800005en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherNihon Univ, School Dentistryen_US
dc.relation.ispartofJournal of Oral Scienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240831_Uen_US
dc.subjectAntioxidanten_US
dc.subjectCalcium Hydroxideen_US
dc.subjectPulp Cappingen_US
dc.subjectResveratrolen_US
dc.titleBiological and physical properties of calcium hydroxide-based pulp-capping materials and their modificationsen_US
dc.typeArticleen_US

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