Prevalence of cypress pollen sensitization and its clinical importance in Izmir, Turkey, with cypress allergy assessed by nasal provocation

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dc.contributor.authorSin, A. Z.
dc.contributor.authorErsoy, R.
dc.contributor.authorGulbahar, O.
dc.contributor.authorArdeniz, O.
dc.contributor.authorGokmen, N. M.
dc.contributor.authorKokuludag, A.
dc.date.accessioned2019-10-27T19:57:11Z
dc.date.available2019-10-27T19:57:11Z
dc.date.issued2008
dc.departmentEge Üniversitesien_US
dc.description.abstractBackground and objective: Pollens from the Cupressaceae family are considered important allergens in the Mediterranean area, though reports of the prevalence of allergic symptoms have ranged from 1.04% to 35.4%. Our aim was to detect the prevalence of cypress pollen sensitization and determine its clinical importance in patients with seasonal respiratory allergy. Methods: We used skin prick tests (SPT) and serum specific IgE assays to reveal sensitization to cypress pollen. In patients who showed positive results to cypress pollen, a nasal provocation test (NPT) with pollen extract was used to assess the target organ response. Results: Sixty-five (14.3%) of 455 patients showed positive SPT responses to Cupressus sempervirens extract. Only I patient was monosensitized while 64 patients were polysensitized. Among those, 2 pollen cosensitizations were found to be significant (86% were cosensitized to grasses and 72% were cosensitized to olive (P <.001). Serum specific IgE to cypress pollen was measured in 50 of the 65 patients; findings were positive for 37. When these 37 patients underwent NPT with C sempervirens allergen extract, only the single monosensitized patient had a positive NPT. Conclusion: A positive SPT to cypress pollen may not reflect the true prevalence of sensitization. We assume that in the absence of a positive NPT, positive SPT results might be related to the presence of cross-reactivity between pollen species.en_US
dc.identifier.endpage51en_US
dc.identifier.issn1018-9068
dc.identifier.issue1en_US
dc.identifier.pmid18361102en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage46en_US
dc.identifier.urihttps://hdl.handle.net/11454/40919
dc.identifier.volume18en_US
dc.identifier.wosWOS:000253388600008en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherEsmon Publicidad S Aen_US
dc.relation.ispartofJournal of Investigational Allergology and Clinical Immunologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectallergyen_US
dc.subjectcypress pollenen_US
dc.subjectcross-reactivityen_US
dc.subjectnasal provocationen_US
dc.titlePrevalence of cypress pollen sensitization and its clinical importance in Izmir, Turkey, with cypress allergy assessed by nasal provocationen_US
dc.typeArticleen_US

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