Prevalence of cypress pollen sensitization and its clinical importance in Izmir, Turkey, with cypress allergy assessed by nasal provocation
Küçük Resim Yok
Tarih
2008
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Esmon Publicidad S A
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Background and objective: Pollens from the Cupressaceae family are considered important allergens in the Mediterranean area, though reports of the prevalence of allergic symptoms have ranged from 1.04% to 35.4%. Our aim was to detect the prevalence of cypress pollen sensitization and determine its clinical importance in patients with seasonal respiratory allergy. Methods: We used skin prick tests (SPT) and serum specific IgE assays to reveal sensitization to cypress pollen. In patients who showed positive results to cypress pollen, a nasal provocation test (NPT) with pollen extract was used to assess the target organ response. Results: Sixty-five (14.3%) of 455 patients showed positive SPT responses to Cupressus sempervirens extract. Only I patient was monosensitized while 64 patients were polysensitized. Among those, 2 pollen cosensitizations were found to be significant (86% were cosensitized to grasses and 72% were cosensitized to olive (P <.001). Serum specific IgE to cypress pollen was measured in 50 of the 65 patients; findings were positive for 37. When these 37 patients underwent NPT with C sempervirens allergen extract, only the single monosensitized patient had a positive NPT. Conclusion: A positive SPT to cypress pollen may not reflect the true prevalence of sensitization. We assume that in the absence of a positive NPT, positive SPT results might be related to the presence of cross-reactivity between pollen species.
Açıklama
Anahtar Kelimeler
allergy, cypress pollen, cross-reactivity, nasal provocation
Kaynak
Journal of Investigational Allergology and Clinical Immunology
WoS Q Değeri
N/A
Scopus Q Değeri
Q3
Cilt
18
Sayı
1
