The effects of morphine and fentanyl alone or in combination added to intrathecal bupivacaine in spinal anesthesia for cesarean section

dc.contributor.authorKaraman S.
dc.contributor.authorGünüsen I.
dc.contributor.authorUyar M.
dc.contributor.authorBiricik E.
dc.contributor.authorFirat V.
dc.date.accessioned2019-10-26T22:11:11Z
dc.date.available2019-10-26T22:11:11Z
dc.date.issued2011
dc.departmentEge Üniversitesien_US
dc.description.abstractObjectives: This randomized double-blind controlled trial examined the efFects of fentanyl and morphine, alone and in combination, as adjuncts to spinal anesthesia for elective cesarean section. Methods: Sixty women undergoing elective cesarean section, with spinal anesthesia using 0.5% hyperbaric bupivacaine, were randomly allocated to receive morphine 0.2 mg, fentanyl 25 µg, or fentanyl 12.5 µg plus morphine 0.1 mg, intrathecally. The start of spinal block, the time to TIO level, the highest sensorial and motor block level, time to regression of sensory block to TIO, time to resolution of motor block, surgical characteristics, maternal side efFects, Apgar and NACS scores, umbilical blood gas evaluations, and time to first analgesic requirement were recorded. Results: No patient experienced pain during the intraoperative period. The degree and time of sensorial and motor block were similar in both groups, and there was no difference in time to TlO level and time to reversal of motor block. The difference in time to first postoperative analgesic requirement was statistically significant. There was no difference between groups in postoperative side efFects. There were no neonatal differences in Apgar and NACS scores or umbilical blood gas evaluations. Conclusion: The quality of postoperative analgesia with morphine, when used alone, was found to be superior to that with fentanyl. The combination of opioids offered no advantages over morphine alone.en_US
dc.identifier.doi10.5505/agri.2011.44127
dc.identifier.endpage63en_US
dc.identifier.issn1300-0012
dc.identifier.issue2en_US
dc.identifier.pmid21644105en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage57en_US
dc.identifier.urihttps://doi.org/10.5505/agri.2011.44127
dc.identifier.urihttps://hdl.handle.net/11454/19330
dc.identifier.volume23en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofAgrien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCesarean sectionen_US
dc.subjectFentanylen_US
dc.subjectIntrathecal bupivacaineen_US
dc.subjectMorphine/fentanylen_US
dc.subjectMorptiineen_US
dc.titleThe effects of morphine and fentanyl alone or in combination added to intrathecal bupivacaine in spinal anesthesia for cesarean sectionen_US
dc.typeArticleen_US

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