The efficacy of intrathecal morphine in post-thoracotomy pain management

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dc.contributor.authorAskar, F. Z.
dc.contributor.authorKocabas, S.
dc.contributor.authorYucel, S.
dc.contributor.authorSamancilar, O.
dc.contributor.authorCetin, H. Y.
dc.contributor.authorUyar, M.
dc.date.accessioned2019-10-27T19:34:52Z
dc.date.available2019-10-27T19:34:52Z
dc.date.issued2007
dc.departmentEge Üniversitesien_US
dc.description.abstractThis study compared the analgesic efficacy of intrathecal (IT) morphine plus IV patient-controlled analgesia (PCA) morphine with IV PCA morphine alone in 33 patients undergoing thoracotomy randomized to two groups: the IT morphine group (n = 17) received 10 mu g/kg morphine 1 h before the end of surgery, while the control group (n = 16) did not. All patients had access to an IV PCA pump post-operatively that delivered 2 mg morphine boluses. Post-operative pain and sedation scores, respiratory and haemodynamic parameters, and morphine demand and delivery were assessed up to 48 h. Post-operative pain scores and morphine consumption were significantly reduced, while peak expiratory flow rates were significantly increased in the IT morphine group compared with controls. We concluded that IT morphine in addition to IV PCA established superior analgesia and maintained better respiratory function compared with IV PCA alone in post-thoracotomy patients.en_US
dc.identifier.doi10.1177/147323000703500305en_US
dc.identifier.endpage322en_US
dc.identifier.issn0300-0605
dc.identifier.issue3en_US
dc.identifier.pmid17593859en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage314en_US
dc.identifier.urihttps://doi.org/10.1177/147323000703500305
dc.identifier.urihttps://hdl.handle.net/11454/39663
dc.identifier.volume35en_US
dc.identifier.wosWOS:000247384700005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherCambridge Med Publen_US
dc.relation.ispartofJournal of International Medical Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectmorphineen_US
dc.subjectopioid analgesicen_US
dc.subjectintravenous patient-controlled analgesiaen_US
dc.subjectintrathecal analgesiaen_US
dc.subjectthoracotomyen_US
dc.subjectpost-thoracotomy painen_US
dc.titleThe efficacy of intrathecal morphine in post-thoracotomy pain managementen_US
dc.typeArticleen_US

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