The efficacy of intrathecal morphine in post-thoracotomy pain management
Küçük Resim Yok
Tarih
2007
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Cambridge Med Publ
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
This study compared the analgesic efficacy of intrathecal (IT) morphine plus IV patient-controlled analgesia (PCA) morphine with IV PCA morphine alone in 33 patients undergoing thoracotomy randomized to two groups: the IT morphine group (n = 17) received 10 mu g/kg morphine 1 h before the end of surgery, while the control group (n = 16) did not. All patients had access to an IV PCA pump post-operatively that delivered 2 mg morphine boluses. Post-operative pain and sedation scores, respiratory and haemodynamic parameters, and morphine demand and delivery were assessed up to 48 h. Post-operative pain scores and morphine consumption were significantly reduced, while peak expiratory flow rates were significantly increased in the IT morphine group compared with controls. We concluded that IT morphine in addition to IV PCA established superior analgesia and maintained better respiratory function compared with IV PCA alone in post-thoracotomy patients.
Açıklama
Anahtar Kelimeler
morphine, opioid analgesic, intravenous patient-controlled analgesia, intrathecal analgesia, thoracotomy, post-thoracotomy pain
Kaynak
Journal of International Medical Research
WoS Q Değeri
Q4
Scopus Q Değeri
N/A
Cilt
35
Sayı
3
