Coexistence of gastric cancer and gastrointestinal stromal tumor: Report of two cases

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dc.contributor.authorFirat, Ozgur
dc.contributor.authorCaliskan, Cemil
dc.contributor.authorKaraca, Can
dc.contributor.authorSezak, Murat
dc.contributor.authorOzutemiz, Omer
dc.contributor.authorErsin, Sinan
dc.contributor.authorGuler, Adem
dc.date.accessioned2019-10-27T21:15:31Z
dc.date.available2019-10-27T21:15:31Z
dc.date.issued2010
dc.departmentEge Üniversitesien_US
dc.description.abstractGastrointestinal stromal tumors and adenocancers are distinct neoplasms originating from different cell layers. Though adenocancers constitute the most common type of gastric tumors, synchronous development of a gastrointestinal stromal tumor is extremely rare. Case 1: A 63-year-old male patient underwent a radical total gastrectomy with D2 lymphadenectomy and Rouxen-Y reconstruction. Histopathologic and immunohistochemical examination of the specimen disclosed an advanced stage, intestinal type adenocancer intermixing with a distinct lesion of gastrointestinal stromal tumor. The early postoperative course was uneventful; however, recurrence was seen and he survived only 13 months. Case 2: A 60-year-old male patient underwent a distal subtotal gastrectomy with D2 lymphadenectomy, and reconstruction was provided with Billroth 2 procedure. Intra-operatively, a 0.5 cm vegetating lesion was detected on the gastric body and resected. Histopathologic and immunohistochemical examination disclosed an intestinal type adenocancer, and the incidental lesion was reported as gastrointestinal stromal tumor. His postoperative course was uneventful, and the patient is free of disease after one year. The conditions under which the synchronous tumors develop away from each other or collide are vague. Currently, the stage of the adenocancer and the size and mitotic manner of the gastrointestinal stromal tumors are the leading prognostic factors.en_US
dc.identifier.doi10.4318/tjg.2010.0105
dc.identifier.endpage304en_US
dc.identifier.issn1300-4948
dc.identifier.issue3en_US
dc.identifier.pmid20931437en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage302en_US
dc.identifier.urihttps://doi.org/10.4318/tjg.2010.0105
dc.identifier.urihttps://hdl.handle.net/11454/43546
dc.identifier.volume21en_US
dc.identifier.wosWOS:000283606300018en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish Soc Gastroenterologyen_US
dc.relation.ispartofTurkish Journal of Gastroenterologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSynchronous gastric tumorsen_US
dc.subjectcollisionen_US
dc.titleCoexistence of gastric cancer and gastrointestinal stromal tumor: Report of two casesen_US
dc.typeArticleen_US

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