Pituitary apoplexy in an adrenocorticotropin-producing pituitary macroadenoma

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dc.contributor.authorSahin, Serap Baydur
dc.contributor.authorCetinkalp, S.
dc.contributor.authorErdogan, M.
dc.contributor.authorCavdar, U.
dc.contributor.authorDuygulu, G.
dc.contributor.authorSaygili, F.
dc.contributor.authorYilmaz, C.
dc.contributor.authorOzgen, A. G.
dc.date.accessioned2019-10-27T21:14:32Z
dc.date.available2019-10-27T21:14:32Z
dc.date.issued2010
dc.departmentEge Üniversitesien_US
dc.description.abstractAdrenocorticotropin (ACTH) producing macroadenomas and pituitary apoplexy are unusual in Cushing's disease. A 20-year-old man who had been diagnosed Cushing's disease 2 months ago, presented with sudden headache, nausea, and vomiting. His serum cortisol level was 0.4 mu g/dl and ACTH level was 23.9 pg/ml. Magnetic resonance imaging of the pituitary gland disclosed a hemorrhage in the pituitary macroadenoma (22 x 19 mm). He was treated with IV methylprednisolone immediately and then the symptoms were relieved within the first day of the treatment. The hemorrhagic lesion was resected by transsphenoidal surgery successfully. Impaired secretion of pituitary hormones may be seen after the pituitary apoplexy. We communicate a case with pituitary apoplexy of an ACTH secreting pituitary macroadenoma, causing acute glucocorticoid insufficiency.en_US
dc.identifier.doi10.1007/s12020-010-9367-8en_US
dc.identifier.endpage146en_US
dc.identifier.issn1355-008X
dc.identifier.issn1559-0100
dc.identifier.issue2en_US
dc.identifier.pmid21046475en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage143en_US
dc.identifier.urihttps://doi.org/10.1007/s12020-010-9367-8
dc.identifier.urihttps://hdl.handle.net/11454/43400
dc.identifier.volume38en_US
dc.identifier.wosWOS:000284115500001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherHumana Press Incen_US
dc.relation.ispartofEndocrineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPituitary apoplexyen_US
dc.subjectPituitary macroadenomaen_US
dc.subjectCushing's diseaseen_US
dc.subjectGlucocorticoid insufficiencyen_US
dc.titlePituitary apoplexy in an adrenocorticotropin-producing pituitary macroadenomaen_US
dc.typeArticleen_US

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