Pituitary apoplexy in an adrenocorticotropin-producing pituitary macroadenoma
Küçük Resim Yok
Tarih
2010
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Humana Press Inc
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Adrenocorticotropin (ACTH) producing macroadenomas and pituitary apoplexy are unusual in Cushing's disease. A 20-year-old man who had been diagnosed Cushing's disease 2 months ago, presented with sudden headache, nausea, and vomiting. His serum cortisol level was 0.4 mu g/dl and ACTH level was 23.9 pg/ml. Magnetic resonance imaging of the pituitary gland disclosed a hemorrhage in the pituitary macroadenoma (22 x 19 mm). He was treated with IV methylprednisolone immediately and then the symptoms were relieved within the first day of the treatment. The hemorrhagic lesion was resected by transsphenoidal surgery successfully. Impaired secretion of pituitary hormones may be seen after the pituitary apoplexy. We communicate a case with pituitary apoplexy of an ACTH secreting pituitary macroadenoma, causing acute glucocorticoid insufficiency.
Açıklama
Anahtar Kelimeler
Pituitary apoplexy, Pituitary macroadenoma, Cushing's disease, Glucocorticoid insufficiency
Kaynak
Endocrine
WoS Q Değeri
Q4
Scopus Q Değeri
Q2
Cilt
38
Sayı
2
