A mutagenicity investigation of sediment from Izmir Inner Bay using Ames genotoxicity assay

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dc.contributor.authorEguz, Yiğit
dc.contributor.authorBoyacıoğlu, Meltem
dc.date.accessioned2024-08-25T18:39:11Z
dc.date.available2024-08-25T18:39:11Z
dc.date.issued2023
dc.departmentEge Üniversitesien_US
dc.description.abstractIzmir Bay is one of the most important ecosystems of Aegean Region. Impacts of environmental pollution in the aquatic environments, especially impacts of pollution with mutagenic and carcinogenic substances on human health is an important area of research. Thus, it is required to incorporate shortterm biological research methods to the molecular chemical analysis methods. By means of Ames's assay, it is possible to determine mutagenic potential of several chemicals, environmental pollutants, sediments, and waste waters. After the treatment facility was established in Izmir Bay in 2000, no mutagenicity studies were carried out in the sediment. Ames's mutagenicity assay without S9 fraction using TA98 and TA100 strains of Salmonella typhimurium was done at four different concentrations (125 mu g, 250 mu g, 375 mu g, and 500 mu g) in the sediment samples from six stations on Izmir Inner Bay in order to detect presence of chemicals that may cause mutagenic effects. Based on the results of Ames's assay, it was found that especially Turan Area (Station 3, on which shipyard is located) among 6 stations on Izmir Bay was under mutagenic and toxic effect and Bostanli Area (Station 6) was under intense toxic effect. Turan Area was under the influence of environmental pollutants that may cause frameshift mutations. According to the present study, Izmir Inner Bay was contaminated by mutagenic and toxic substances.en_US
dc.description.sponsorshipCoordination Board for Scientific Research Projects of Ege University [FGA-2019-20553]en_US
dc.description.sponsorshipThe present study was supported with project numbered FGA-2019-20553 by the Coordination Board for Scientific Research Projects of Ege University. We would like to thank them for their contribution.en_US
dc.identifier.doi10.12714/egejfas.40.3.08
dc.identifier.endpage218en_US
dc.identifier.issn1300-1590
dc.identifier.issn2148-3140
dc.identifier.issue3en_US
dc.identifier.startpage211en_US
dc.identifier.trdizinid1210981en_US
dc.identifier.urihttps://doi.org/10.12714/egejfas.40.3.08
dc.identifier.urihttps://hdl.handle.net/11454/101275
dc.identifier.volume40en_US
dc.identifier.wosWOS:001093900200008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherEge Univ, Fac Fisheriesen_US
dc.relation.ispartofSu Urunleri Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240825_Gen_US
dc.subjectSalmonella typhimuriumen_US
dc.subjectTA98-TA100en_US
dc.subjectsedimenten_US
dc.subjectpollutionen_US
dc.subjectAmes testen_US
dc.subjectIzmir Bayen_US
dc.subjectMussels Mytilus-Galloprovincialisen_US
dc.subjectHeavy-Metalen_US
dc.subjectChemical-Analysisen_US
dc.subjectWater Samplesen_US
dc.subjectSalmonellaen_US
dc.subjectPollutionen_US
dc.titleA mutagenicity investigation of sediment from Izmir Inner Bay using Ames genotoxicity assayen_US
dc.typeArticleen_US

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