A mutagenicity investigation of sediment from Izmir Inner Bay using Ames genotoxicity assay
Küçük Resim Yok
Tarih
2023
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Ege Univ, Fac Fisheries
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Izmir Bay is one of the most important ecosystems of Aegean Region. Impacts of environmental pollution in the aquatic environments, especially impacts of pollution with mutagenic and carcinogenic substances on human health is an important area of research. Thus, it is required to incorporate shortterm biological research methods to the molecular chemical analysis methods. By means of Ames's assay, it is possible to determine mutagenic potential of several chemicals, environmental pollutants, sediments, and waste waters. After the treatment facility was established in Izmir Bay in 2000, no mutagenicity studies were carried out in the sediment. Ames's mutagenicity assay without S9 fraction using TA98 and TA100 strains of Salmonella typhimurium was done at four different concentrations (125 mu g, 250 mu g, 375 mu g, and 500 mu g) in the sediment samples from six stations on Izmir Inner Bay in order to detect presence of chemicals that may cause mutagenic effects. Based on the results of Ames's assay, it was found that especially Turan Area (Station 3, on which shipyard is located) among 6 stations on Izmir Bay was under mutagenic and toxic effect and Bostanli Area (Station 6) was under intense toxic effect. Turan Area was under the influence of environmental pollutants that may cause frameshift mutations. According to the present study, Izmir Inner Bay was contaminated by mutagenic and toxic substances.
Açıklama
Anahtar Kelimeler
Salmonella typhimurium, TA98-TA100, sediment, pollution, Ames test, Izmir Bay, Mussels Mytilus-Galloprovincialis, Heavy-Metal, Chemical-Analysis, Water Samples, Salmonella, Pollution
Kaynak
Su Urunleri Dergisi
WoS Q Değeri
Q4
Scopus Q Değeri
Cilt
40
Sayı
3
