Antibacterial resistance patterns and incidence of hospital-acquired Staphylococcus aureus bacteremia in a tertiary care educational hospital in Turkey: a perspective from 2001 to 2013

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dc.contributor.authorSipahi, Oguz Resat
dc.contributor.authorUysal, Serhat
dc.contributor.authorAydemir, Sabire Sohret
dc.contributor.authorPullukcu, Husnu
dc.contributor.authorTasbakan, Meltem
dc.contributor.authorTunger, Alper
dc.contributor.authorCilli, Fatma Feriha
dc.contributor.authorYamazhan, Tansu
dc.contributor.authorArda, Bilgin
dc.contributor.authorSipahi, Hilal
dc.contributor.authorUlusoy, Sercan
dc.date.accessioned2019-10-27T11:20:55Z
dc.date.available2019-10-27T11:20:55Z
dc.date.issued2017
dc.departmentEge Üniversitesien_US
dc.description.abstractBackground/aim: Staphylococcus aureus is an important nosocomial pathogen and a successful antimicrobial-resistance developer. In this study we retrospectively evaluated the resistance patterns and incidence of microbiologically confirmed nosocomial bacteremia (MCNB) related S. aureus strains between 2001 and 2013. Materials and methods: Any patient in whom S. aureus was isolated in at least one set of blood cultures (sent to the bacteriology laboratory 72 h after hospital admission) was considered to have MCNB. Results: The methicillin-resistant S. aureus (MRSA) rate in 2001 was 73.8% whereas it was 36.2% in 2013. When the 2001-2003 and 2011-2013 periods were compared, resistance to oxacillin, levofloxacin, gentamicin, erythromycin, and clindamycin decreased significantly (P < 0.05). When we evaluated the total S. aureus, MRSA, and methicillin-sensitive S. aureus (MSSA) bacteremia rates per 1000 days and 1000 patients, there was an increase in the 2004-2005 period, which was followed by a slight decrease until 2013 (P < 0.05). There was a plateau in MCNB-related S. aureus rates between 2008 and 2011. Conclusion: There was a decrease in overall S. aureus and MRSA bacteremia incidence as well as MRSA rates except for a plateau between 2008 and 2011. This steady decrease in the resistance rates is most probably due to the 2003 budget application and application of antimicrobial stewardship.en_US
dc.identifier.doi10.3906/sag-1607-63
dc.identifier.endpage1215en_US
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue4en_US
dc.identifier.pmid29156865en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1210en_US
dc.identifier.urihttps://doi.org/10.3906/sag-1607-63
dc.identifier.urihttps://hdl.handle.net/11454/32884
dc.identifier.volume47en_US
dc.identifier.wosWOS:000408336600025en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTubitak Scientific & Technical Research Council Turkeyen_US
dc.relation.ispartofTurkish Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAntimicrobial resistance epidemiologyen_US
dc.subjectbacteremiaen_US
dc.subjectStaphylococcus aureusen_US
dc.subjectMRSAen_US
dc.subjectinfectious diseasesen_US
dc.subjecterythromycinen_US
dc.subjectglycopeptidesen_US
dc.subjectvancomycinen_US
dc.subjectteicoplaninen_US
dc.subjectincidenceen_US
dc.titleAntibacterial resistance patterns and incidence of hospital-acquired Staphylococcus aureus bacteremia in a tertiary care educational hospital in Turkey: a perspective from 2001 to 2013en_US
dc.typeArticleen_US

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