Effect of Tamsulosin on Corneal Biomechanical Features

Basit Öğe Kaydı
dc.contributor.authorOnay, Melis Palamar
dc.contributor.authorEmre, Sinan
dc.contributor.authorTurna, Burat
dc.contributor.authorYağcı, Ayşe
dc.date.accessioned2020-12-01T12:26:08Z
dc.date.available2020-12-01T12:26:08Z
dc.date.issued2016
dc.departmentEge Üniversitesien_US
dc.description.abstractAAmmaaççen_US
dc.description.abstractObjective: Tamsulosin (Flomax®) usage was reported to increase central corneal thickness (CCT). As CCT and ocular biomechanical parameters are closely related, this study was conducted to investigate the possible effects of tamsulosin on biomechanical parameters of cornea as measured with Reichert Ocular Response Analyser (ORA) in patients with benign prostate hyperplasia. Material and Methods: Besides full eye examination (best corrected visual acuity, intraocular pressure (IOP) measured with Goldmann applanation tonometry, CCT) ORA (corneal hysteresis, corneal resistance factor, corneal compensated IOP, Goldmann correlated IOP) measurements of 30 eyes of 15 male patients before and one month after tamsulosin therapy were performed. For comparisons paired t-test was used. Results: Mean age in the study group was 61.50±6.10 (range 47-69) years. Pre-tamsulosin CCT was lower than post-tamsulosin values (pre-: 549.18±28.84 micrometers, post-: 556.77±24.86 micrometers; p=0.002). Although statistically insignificant corneal resistance factor after tamsulosin use was lower (pre-: 10.73±1.05 mmHg, post-: 9.45±1.51 mmHg; p=0.071). Measurements before and after tamsulosin treatment was not statistically different for any of the other parameters. Conclusion: Tamsulosin seems not only to cause an increment on CCT, but also effect corneal resistance factor. the long term effects of tamsulosin on corneal biomechanical properties should further be investigated with larger group of patients.en_US
dc.identifier.endpage61en_US
dc.identifier.issn1300-0365
dc.identifier.issn2146-9008
dc.identifier.issue1en_US
dc.identifier.startpage57en_US
dc.identifier.urihttps://app.trdizin.gov.tr//makale/TWpnME1qZ3pNdz09
dc.identifier.urihttps://hdl.handle.net/11454/65509
dc.identifier.volume25en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofTürkiye Klinikleri Oftalmoloji Dergisien_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGöz Hastalıklarıen_US
dc.titleEffect of Tamsulosin on Corneal Biomechanical Featuresen_US
dc.title.alternativeTamsulosinin Korneanın Biyomekanik Özellikleri Üzerine Etkisien_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

TR-Dizin İndeksli Yayınlar Koleksiyonu