Cytosine-type nucleosides from marine-derived Streptomyces rochei 06CM016
Küçük Resim Yok
Tarih
2016
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Japan Antibiotics Research Assoc
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Rocheicoside A (3), a nucleoside analog possessing a novel 5-(hydroxymethyl)-5-methylimidazolidin-4-one substructure, was isolated from marine-derived actinomycete Streptomyces rochei 06CM016, together with a new (4) and three known compounds. Structures of the new metabolites were elucidated by one-dimensional (H-1 and C-13) and 2D NMR (COSY, HMQC and HMBC) and HR-TOF-MS analyses. All the metabolites exhibited significant antimicrobial activity. A plausible mechanism was proposed for compound 3's formation from amicetin.
Açıklama
Anahtar Kelimeler
Kaynak
Journal of Antibiotics
WoS Q Değeri
Q2
Scopus Q Değeri
Q2
Cilt
69
Sayı
1
