Comparative analysis of protein profiles in skin secretions of some Rana species: Preliminary insights into antimicrobial activity

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dc.authorid0000-0002-0226-9332
dc.authorid0000-0002-2667-8106
dc.authorid0000-0003-2572-7508
dc.contributor.authorTanriverdi, O. Ebru
dc.contributor.authorAyaz, Dincer
dc.contributor.authorTerzi, Yigit
dc.date.accessioned2025-04-24T12:37:54Z
dc.date.available2025-04-24T12:37:54Z
dc.date.issued2024
dc.departmentEge Üniversitesi, Fen Fakültesi, Biyoloji Bölümü
dc.description.abstractProtein profiles of skin secretions of Rana dalmatina (Agile Frog), Rana macrocnemis (Uludag Frog), Rana tavasensis (Tavas Frog) and Rana holtzi (Taurus Frog) frog species belonging to the Rana genus distributed in the Anatolian region of Turkiye were determined for the first time using the Tricine-SDS-PAGE Electrophoresis method and Coomassie Brilliant Blue (CBB) staining. By the results, some peptides with mass <5 kDa were detected. Just one peptide with mass <5 kDa was found in the secretion of each R. dalmatina, R. macrocnemis, and R. tavasensis while there was two in R. holtzi secretion. The antibacterial activity of secretions was determined using plate well diffusion assay on E. coli, S. typhimurium, S. aureus, B. cereus and L. monocytogenes bacteria. R. dalmatina created the inhibition zone for S. typhimurium, S. aureus, B. cereus, and L. monocytogenes. The zones of inhibition by R. tavasensis and R. macrocnemis species secretions were observed on S. aureus, B. cereus, and L. monocytogenes. It was found that R. holtzi creates an inhibition zone only on B. cereus. The results showed that the secretion of none of the species doesn't have antibacterial activity on E. coli. The skin secretion of R. dalmatina showed the most activity against bacteria, while R. holtzi had the least.
dc.identifier.citationTanrıverdi O, E., Ayaz, D., & Terzi, Y. (2024). Comparative analysis of protein profiles in skin secretions of some rana species: Preliminary insights into antimicrobial activity. Toxicon (Oxford), 250, 108110.
dc.identifier.doi10.1016/j.toxicon.2024.108110
dc.identifier.endpage8
dc.identifier.issn00410101
dc.identifier.issueNov
dc.identifier.pmid39343149
dc.identifier.scopus2-s2.0-85205312495
dc.identifier.scopusqualityQ2
dc.identifier.startpage1
dc.identifier.urihttps://doi.org/10.1016/j.toxicon.2024.108110
dc.identifier.urihttps://hdl.handle.net/11454/117149
dc.identifier.wosWOS:001343455400001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorTanriverdi, O. Ebru
dc.institutionauthorAyaz, Dincer
dc.institutionauthorTerzi, Yigit
dc.institutionauthorid0000-0002-0226-9332
dc.institutionauthorid0000-0002-2667-8106
dc.institutionauthorid0000-0003-2572-7508
dc.language.isoen
dc.publisherPergamon-Elsevier Science Ltd
dc.relation.ispartofToxicon
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAntimicrobial peptides
dc.subjectR. dalmatina
dc.subjectR. holtzi
dc.subjectR. macrocnemis
dc.subjectR. tavasensis
dc.subjectTricine-SDS- PAGE
dc.titleComparative analysis of protein profiles in skin secretions of some Rana species: Preliminary insights into antimicrobial activity
dc.typeArticle

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