Accumulation of 99tcm-polyclonal immunoglobulin in different stages of infection: An experimental study

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dc.contributor.authorBurak Z.
dc.contributor.authorözcan Z.B.
dc.contributor.authorErdem S.
dc.contributor.authorArgon M.
dc.contributor.authorDuman Y.
dc.contributor.authorErdener A.
dc.contributor.authorözcan C.
dc.contributor.authorözacar T.
dc.contributor.authorBasdemir G.
dc.date.accessioned2019-10-27T09:00:48Z
dc.date.available2019-10-27T09:00:48Z
dc.date.issued1996
dc.departmentEge Üniversitesien_US
dc.description.abstractIn this experimental study, the utility of 99Tcm-polyclonal human immunoglobulin (99Tcm-HIG) for localizing acute and chronic phases of inflammatory lesions was investigated. Three groups of rats were inoculated with Staphylococcus aureus in the right thigh. Then, 24 h (group I, n = 12), 48 h (group II, n = 12) and 72 h (group III, n = 12) post-inoculation, the rats received 40 MBq 99Tcm-HIG into the jugular vein. In addition, two control rats were studied at 24 h after inoculation of sterile saline. Both visual and quantitative evaluations were undertaken. The acute and chronic stages of inflammation were determined by pathological examination. The mean (±s.d.) lesion/contralateral uptake ratios at 4 and 24 h after 99Tcm-HIG injection were: group I,1.22 ± 0.1 and 2.12 ± 0.16; group II, 1.15 ± 0.08 and 2.25 ± 0.16; group III, 1.06 ± 0.09 and 2.08 ± 0.14. In conclusion, the acute and chronic phases of infection showed non-significant differences in 99Tcm-HIG uptake ratios. © 1996 Chapman and Hall Ltd.en_US
dc.identifier.doi10.1097/00006231-199605000-00013en_US
dc.identifier.endpage434en_US
dc.identifier.issn0143-3636
dc.identifier.issue5en_US
dc.identifier.pmid8736521en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage430en_US
dc.identifier.urihttps://doi.org/10.1097/00006231-199605000-00013
dc.identifier.urihttps://hdl.handle.net/11454/28129
dc.identifier.volume17en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofNuclear Medicine Communicationsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleAccumulation of 99tcm-polyclonal immunoglobulin in different stages of infection: An experimental studyen_US
dc.typeArticleen_US

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