Biological investigation of I-131-labeled new water soluble Ru(II) polypyridyl complex

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dc.contributor.authorOcakoglu, Kasim
dc.contributor.authorYildrim, Yeliz
dc.contributor.authorLambrecht, Fatma Yurt
dc.contributor.authorOcal, Jale
dc.contributor.authorIcli, Siddik
dc.date.accessioned2019-10-27T19:55:25Z
dc.date.available2019-10-27T19:55:25Z
dc.date.issued2008
dc.departmentEge Üniversitesien_US
dc.description.abstractNew [Ru(L1)(dcbpy)(NCS)(2)] complex was synthesized in a one-pot reaction starting from [RuCl2(p-cymene)](2), where the ligands (dcbpy = 4,4'-dicarboxy-2,2'-bipyridine, L1 = dipyrido[3,2-a:2',3'-c]phenazine-11-ylcarbonyl) -sodium) are introduced sequentially. The resulting complex was characterized by IR, NMR, and elemental analysis. The complex was labeled with I-131. Biodistribution study of the complex was carried out using I-131-labeled [Ru(L1)(dcbpy)(NCS)(2)] complex. The biodistribution study performed with albino Wistar male rats has shown that the complex has high uptake in the lung, small intestine, fat, and spleen. (C) 2007 Elsevier Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.apradiso.2007.07.033en_US
dc.identifier.endpage121en_US
dc.identifier.issn0969-8043
dc.identifier.issue2en_US
dc.identifier.pmid17913501en_US
dc.identifier.startpage115en_US
dc.identifier.urihttps://doi.org/10.1016/j.apradiso.2007.07.033
dc.identifier.urihttps://hdl.handle.net/11454/40680
dc.identifier.volume66en_US
dc.identifier.wosWOS:000253103100001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.ispartofApplied Radiation and Isotopesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectruthenium complexesen_US
dc.subjectpolypyridyl complexesen_US
dc.subjectphotosensitizersen_US
dc.subjectcharge transfer sensitizeren_US
dc.subjectI-131en_US
dc.subjectI-131-labeled ruthenium complexen_US
dc.titleBiological investigation of I-131-labeled new water soluble Ru(II) polypyridyl complexen_US
dc.typeArticleen_US

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