Preparation and Characterization of Cumin Essential Oil Nanoemulsion (CEONE) as an Antibacterial Agent and Growth Promoter in Broilers: A Study on Efficacy, Safety, and Health Impact

Basit Öğe Kaydı
dc.authorid0000-0001-6470-2608
dc.contributor.authorJabbar, Muhammad
dc.contributor.authorBaboo, Irfan
dc.contributor.authorMajeed, Hamid
dc.contributor.authorFarooq, Zahid
dc.contributor.authorPalangi, Valiollah
dc.contributor.authorLackner, Maximilian
dc.date.accessioned2025-04-29T11:28:55Z
dc.date.available2025-04-29T11:28:55Z
dc.date.issued2024
dc.departmentEge Üniversitesi, Ziraat Fakültesi, Zootekni Bölümü
dc.description.abstractSimple Summary Broiler meat is widely consumed around the globe. To fulfill consumer demand, broiler farmers are using antibiotic growth promoters for improved efficiency. However, these antibiotics have been banned in developed countries due to antimicrobial resistance. Therefore, plant supplements in the form of essential oils (EOs) have gained acceptability due to their excellent antibacterial properties. The next step is to encapsulate the EO for better delivery to target organs in broilers, which was investigated in vivo. The novelty of this study is to encapsulate volatile compounds of EOs in nanoemulsion (NE). This study has observed a positive effect of NE in terms of broiler growth performance, suggesting that cumin EO NE (CEONE) can be used as a substitute for the prophylactic administration of synthetic antibiotics.Abstract This research characterized and explored the effect of cumin essential oil nanoemulsion (CEONE) on broiler growth performance, serum biochemistry, hematological parameters, and cecal microbial count. Day-old (n = 96) broilers (Ross 308) were randomly assigned to six treatments with five replicates of three broilers each. The dietary treatments consisted of negative control (only basal diet), positive control (basal diet + 200 mu L of enrofloxacin), 25 mu L (basal diet + 25 mu L of CEONE), 50 mu L (basal diet + 50 mu L of CEONE), 75 mu L (basal diet + 75 mu L of CEONE), and 100 mu L (basal diet + 100 mu L of CEONE). The broiler's body weight gain (BWG) after 42 days of treatment exhibited increased weight in the CEONE group (976.47 +/- 11.82-1116.22 +/- 29.04). The gain in weight was further evidenced by the beneficial microbe load (107 log) compared to the pathogenic strain. All the biochemical parameters were observed in the normal range, except for a higher level of HDL and a lower LDL value. This safety has been validated by pKCSM toxicity analysis showing a safe and highly tolerable dose of cuminaldehyde. In conclusion, this research observed the potential of CEONE as a multifunctional agent. It is a valuable candidate for further application in combating bacterial infections and enhancing animal health and growth. on
dc.identifier.citationJabbar, M., Baboo, I., Majeed, H., Farooq, Z., Palangi, V., & Lackner, M. (2024). Preparation and characterization of cumin essential oil nanoemulsion (CEONE) as an antibacterial agent and growth promoter in broilers: A study on efficacy, safety, and health impact. Animals (Basel), 14(19), 2860.
dc.identifier.doi10.3390/ani14192860
dc.identifier.endpage23
dc.identifier.issn20762615
dc.identifier.issue19
dc.identifier.pmid39409810
dc.identifier.scopus85206578845
dc.identifier.scopusqualityQ1
dc.identifier.startpage1
dc.identifier.urihttps://doi.org/10.3390/ani14192860
dc.identifier.urihttps://hdl.handle.net/11454/117179
dc.identifier.volume14
dc.identifier.wosWOS:001331757500001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorPalangi, Valiollah
dc.institutionauthorid0000-0001-6470-2608
dc.language.isoen
dc.publisherMDPI
dc.relation.ispartofAnimals
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectchicken
dc.subjectcuminaldehyde
dc.subjectessential oil
dc.subjectnanoemulsion
dc.titlePreparation and Characterization of Cumin Essential Oil Nanoemulsion (CEONE) as an Antibacterial Agent and Growth Promoter in Broilers: A Study on Efficacy, Safety, and Health Impact
dc.typeArticle

Dosyalar

Lisans paketi
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
license.txt
Boyut:
1.17 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu