Preparation and Characterization of Cumin Essential Oil Nanoemulsion (CEONE) as an Antibacterial Agent and Growth Promoter in Broilers: A Study on Efficacy, Safety, and Health Impact
Küçük Resim Yok
Tarih
2024
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
MDPI
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Simple Summary Broiler meat is widely consumed around the globe. To fulfill consumer demand, broiler farmers are using antibiotic growth promoters for improved efficiency. However, these antibiotics have been banned in developed countries due to antimicrobial resistance. Therefore, plant supplements in the form of essential oils (EOs) have gained acceptability due to their excellent antibacterial properties. The next step is to encapsulate the EO for better delivery to target organs in broilers, which was investigated in vivo. The novelty of this study is to encapsulate volatile compounds of EOs in nanoemulsion (NE). This study has observed a positive effect of NE in terms of broiler growth performance, suggesting that cumin EO NE (CEONE) can be used as a substitute for the prophylactic administration of synthetic antibiotics.Abstract This research characterized and explored the effect of cumin essential oil nanoemulsion (CEONE) on broiler growth performance, serum biochemistry, hematological parameters, and cecal microbial count. Day-old (n = 96) broilers (Ross 308) were randomly assigned to six treatments with five replicates of three broilers each. The dietary treatments consisted of negative control (only basal diet), positive control (basal diet + 200 mu L of enrofloxacin), 25 mu L (basal diet + 25 mu L of CEONE), 50 mu L (basal diet + 50 mu L of CEONE), 75 mu L (basal diet + 75 mu L of CEONE), and 100 mu L (basal diet + 100 mu L of CEONE). The broiler's body weight gain (BWG) after 42 days of treatment exhibited increased weight in the CEONE group (976.47 +/- 11.82-1116.22 +/- 29.04). The gain in weight was further evidenced by the beneficial microbe load (107 log) compared to the pathogenic strain. All the biochemical parameters were observed in the normal range, except for a higher level of HDL and a lower LDL value. This safety has been validated by pKCSM toxicity analysis showing a safe and highly tolerable dose of cuminaldehyde. In conclusion, this research observed the potential of CEONE as a multifunctional agent. It is a valuable candidate for further application in combating bacterial infections and enhancing animal health and growth.
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Açıklama
Anahtar Kelimeler
chicken, cuminaldehyde, essential oil, nanoemulsion
Kaynak
Animals
WoS Q Değeri
Q1
Scopus Q Değeri
Q1
Cilt
14
Sayı
19
Künye
Jabbar, M., Baboo, I., Majeed, H., Farooq, Z., Palangi, V., & Lackner, M. (2024). Preparation and characterization of cumin essential oil nanoemulsion (CEONE) as an antibacterial agent and growth promoter in broilers: A study on efficacy, safety, and health impact. Animals (Basel), 14(19), 2860.
