Immunohistochemical and histopathological evaluation of 2,4-dichlorophenoxyacetic acid-induced changes in rat kidney cortex

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dc.contributor.authorUyanikgil Y.
dc.contributor.authorAteş U.
dc.contributor.authorBaka M.
dc.contributor.authorBiçer S.
dc.contributor.authorÖztaş E.
dc.contributor.authorErgen G.
dc.date.accessioned2019-10-27T08:35:44Z
dc.date.available2019-10-27T08:35:44Z
dc.date.issued2009
dc.departmentEge Üniversitesien_US
dc.description.abstractThis study aims to investigate the effect of 2,4-dichlorophenoxyacetic acid (2,4-D) on rat kidney cortex histology. Oral exposure of rats to 2,4-D for 28 days resulted in decreases in body weight gain and kidney weight. Histological examination showed degeneration in renal corpuscles and podocytes; vacuolization in the glomerulus with disintegration of the basal membrane; tissue edema; vacuolization, cystic dilation and invagination of the basal laminae in the tubular structures; dilation and congestion in renal corpuscular vessels and marked decrease in glomerular and stromal fibronectin reaction; suggesting that subacute 2,4-D administration induces dose-dependent histopathological degenerative effects in rat kidney cortex. © 2009 Springer Science+Business Media, LLC.en_US
dc.identifier.doi10.1007/s00128-009-9689-5en_US
dc.identifier.endpage755en_US
dc.identifier.issn0007-4861
dc.identifier.issue6en_US
dc.identifier.pmid19277441en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage749en_US
dc.identifier.urihttps://doi.org/10.1007/s00128-009-9689-5
dc.identifier.urihttps://hdl.handle.net/11454/27287
dc.identifier.volume82en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofBulletin of Environmental Contamination and Toxicologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject2,4-Den_US
dc.subjectHerbicideen_US
dc.subjectHistopathologyen_US
dc.subjectKidneyen_US
dc.subjectRaten_US
dc.titleImmunohistochemical and histopathological evaluation of 2,4-dichlorophenoxyacetic acid-induced changes in rat kidney cortexen_US
dc.typeArticleen_US

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