Relationship between first trimester aneuploidy screening test serum analytes and placenta accreta

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dc.contributor.authorBuke, Baris
dc.contributor.authorAkkaya, Hatice
dc.contributor.authorDemir, Sibel
dc.contributor.authorSagol, Sermet
dc.contributor.authorSimsek, Deniz
dc.contributor.authorBasol, Gunes
dc.contributor.authorBarutcuoglu, Burcu
dc.date.accessioned2019-10-27T10:47:03Z
dc.date.available2019-10-27T10:47:03Z
dc.date.issued2018
dc.departmentEge Üniversitesien_US
dc.description.abstractObjective: The aim of this study is to determine whether there is a relationship between first trimester serum pregnancy-associated plasma protein A (PAPP-A) and free beta human chorionic gonadotropin (fhCG) MoM values and placenta accreta in women who had placenta previa.Study design: A total of 88 patients with placenta previa who had first trimester aneuploidy screening test results were enrolled in the study. Nineteen of these patients were also diagnosed with placenta accreta. As probable markers of excessive placental invasion, serum PAPP-A and fhCG MoM values were compared in two groups with and without placenta accreta.Results: Patients with placenta accreta had higher statistically significant serum PAPP-A (1.20 versus 0.865, respectively, p=0.045) and fhCG MoM (1.42 versus 0.93, respectively, p=0.042) values than patients without accreta.Conclusions: Higher first trimester serum PAPP-A and fhCG MoM values seem to be associated with placenta accreta in women with placenta previa. Further studies are needed to use these promising additional tools for early detection of placenta accreta.en_US
dc.identifier.doi10.1080/14767058.2016.1275546en_US
dc.identifier.endpage62en_US
dc.identifier.issn1476-7058
dc.identifier.issn1476-4954
dc.identifier.issue1en_US
dc.identifier.pmid28027672en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage59en_US
dc.identifier.urihttps://doi.org/10.1080/14767058.2016.1275546
dc.identifier.urihttps://hdl.handle.net/11454/31376
dc.identifier.volume31en_US
dc.identifier.wosWOS:000415799600010en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofJournal of Maternal-Fetal & Neonatal Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPAPP-Aen_US
dc.subjectfhCGen_US
dc.subjectplacenta accretaen_US
dc.subjectmorbidly adherent placentaen_US
dc.subjectexcessive placentationen_US
dc.titleRelationship between first trimester aneuploidy screening test serum analytes and placenta accretaen_US
dc.typeArticleen_US

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