Relationship between first trimester aneuploidy screening test serum analytes and placenta accreta
Küçük Resim Yok
Tarih
2018
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Taylor & Francis Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective: The aim of this study is to determine whether there is a relationship between first trimester serum pregnancy-associated plasma protein A (PAPP-A) and free beta human chorionic gonadotropin (fhCG) MoM values and placenta accreta in women who had placenta previa.Study design: A total of 88 patients with placenta previa who had first trimester aneuploidy screening test results were enrolled in the study. Nineteen of these patients were also diagnosed with placenta accreta. As probable markers of excessive placental invasion, serum PAPP-A and fhCG MoM values were compared in two groups with and without placenta accreta.Results: Patients with placenta accreta had higher statistically significant serum PAPP-A (1.20 versus 0.865, respectively, p=0.045) and fhCG MoM (1.42 versus 0.93, respectively, p=0.042) values than patients without accreta.Conclusions: Higher first trimester serum PAPP-A and fhCG MoM values seem to be associated with placenta accreta in women with placenta previa. Further studies are needed to use these promising additional tools for early detection of placenta accreta.
Açıklama
Anahtar Kelimeler
PAPP-A, fhCG, placenta accreta, morbidly adherent placenta, excessive placentation
Kaynak
Journal of Maternal-Fetal & Neonatal Medicine
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
31
Sayı
1
