Assessment and outcome of pediatric intestinal pseudo-obstruction: A tertiary-care-center experience from Turkey

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dc.contributor.authorAppak, Yeliz Cagan
dc.contributor.authorBaran, Masallah
dc.contributor.authorOztan, Mustafa Onur
dc.contributor.authorKarakoyun, Miray
dc.contributor.authorTurhan, Soysal
dc.contributor.authorTugmen, Cem
dc.contributor.authorAydogdu, Sema
dc.contributor.authorKaraca, Cezmi
dc.contributor.authorKoyluoglu, Gokhan
dc.date.accessioned2019-10-27T09:45:13Z
dc.date.available2019-10-27T09:45:13Z
dc.date.issued2019
dc.departmentEge Üniversitesien_US
dc.description.abstractBackground/Alms: Pediatric intestinal pseudo-obstruction (PIPO) is a severe disorder of gut motility. In this rare and difficult-to-manage disease, complex treatment method, such as intestinal transplantation, is sometimes needed. This study evaluated the management and follow-up results of patients with PIPO who received treatment at our center. Materials and Methods: The cases of 13 patients with PIPO were reviewed retrospectively. Demographic data, clinical features, etiologies, pharmacological and surgical treatments, nutritional support, anthropometric findings, small bowel transplantation (SBT), and survival rates were assessed. Results: Two of the patients were diagnosed at 1 and 5 years of age, while other patients were diagnosed during neonatal period. The etiological cause could not be identified for 5 patients. Pharmacological treatment response was observed in 38.4% of patients. Post-pyloric feeding was applied in 4 patients, but no response was observed. Gastrostomy decreased the clinical symptoms in 3 patients during the abdominal distension period. Total oral nutrition was achieved in 38.4% of the total-parenteral-nutrition (TPN)-dependent patients. It was observed that anthropometric findings improved in patients with total oral nutrition. Liver cirrhosis developed in 1 patient. Venous thrombosis developed in 4 patients. The SBT was performed on 3 patients. One of these patients has been followed up for the last 4 years. Conclusion: Pediatric intestinal pseudo-obstruction is a rare disease that can present with a wide range of clinical symptoms. While some patients require intestinal transplantation, supportive care may be sufficient in others. For this reason, patients with PIPO should be managed individually.en_US
dc.identifier.doi10.5152/tjg.2019.18287
dc.identifier.endpage363en_US
dc.identifier.issn1300-4948
dc.identifier.issn2148-5607
dc.identifier.issue4en_US
dc.identifier.pmid30666970en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage357en_US
dc.identifier.urihttps://doi.org/10.5152/tjg.2019.18287
dc.identifier.urihttps://hdl.handle.net/11454/29113
dc.identifier.volume30en_US
dc.identifier.wosWOS:000463369400008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAvesen_US
dc.relation.ispartofTurkish Journal of Gastroenterologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectIntestinal pseudo-obstructionen_US
dc.subjectchilden_US
dc.subjectintestinal transplantationen_US
dc.subjectnutritionen_US
dc.subjecttreatmenten_US
dc.titleAssessment and outcome of pediatric intestinal pseudo-obstruction: A tertiary-care-center experience from Turkeyen_US
dc.typeArticleen_US

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