A novel DAD type and folic acid conjugated fluorescent monomer as a targeting probe for imaging of folate receptor overexpressed cells

dc.contributor.authorEkiz Kanik F.
dc.contributor.authorAg D.
dc.contributor.authorSeleci M.
dc.contributor.authorBarlas F.B.
dc.contributor.authorKesik M.
dc.contributor.authorHizalan G.
dc.contributor.authorAkpinar H.
dc.contributor.authorTimur S.
dc.contributor.authorToppare L.
dc.date.accessioned2019-10-27T08:22:28Z
dc.date.available2019-10-27T08:22:28Z
dc.date.issued2014
dc.departmentEge Üniversitesien_US
dc.description.abstractWe describe a modification and post-functionalization technique for a donor-acceptor-donor type monomer; 6-(4,7-bis(2,3-dihydrothieno[3,4-b][1,4]dioxin-5-yl)-2H-benzo[d][1,2, 3]triazol-2-yl)hexan-1-amine. Folic acid was attached to the fluorescent structure. The conjugation was confirmed via NMR and Fourier transform infrared analyses. Cytotoxicity was investigated and the comparison of association of targeted monomeric structures in tumor cells was monitored via fluorescence microscopy. © 2014 American Institute of Chemical Engineers.en_US
dc.identifier.doi10.1002/btpr.1928en_US
dc.identifier.endpage959en_US
dc.identifier.issn8756-7938
dc.identifier.issue4en_US
dc.identifier.pmid24828125en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage952en_US
dc.identifier.urihttps://doi.org/10.1002/btpr.1928
dc.identifier.urihttps://hdl.handle.net/11454/26258
dc.identifier.volume30en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherJohn Wiley and Sons Inc.en_US
dc.relation.ispartofBiotechnology Progressen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCell imagingen_US
dc.subjectConjugationen_US
dc.subjectFluorescence microscopyen_US
dc.subjectFolic aciden_US
dc.titleA novel DAD type and folic acid conjugated fluorescent monomer as a targeting probe for imaging of folate receptor overexpressed cellsen_US
dc.typeArticleen_US

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