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Öğe Bilateral acute iris transillumination: Case report(Elsevier Science Bv, 2016) Degirmenci, Cumali; Yilmaz, Suzan Guven; Palamar, Melis; Ates, HalilBilateral acute iris transillumination (BAIT) is a recently defined disease characterized with bilateral acute, severe pigment dispersion of iris and pupil sphincter paralysis. The etiopathogenesis of the disease is unknown, but antibiotics such as moxifloxacin, clarithromycin, viral infections, and fumigation therapies were considered as probable etiologic factors. A 33-year-old female was referred to our clinic for acute iridocyclitis refractory to azathioprine, colchicum and corticosteroid treatments. Ophthalmic examination revealed bilateral pigment dispersion, significant iris transillumination, heavy pigment deposition in iridocorneal angle, and elevated intraocular pressure. Upon systemic evaluation she was found to have bacterial urinary tract infection. BAIT is an important cause of pigment dispersion and clinicians must be vigilant for this condition to avoid unnecessary diagnostic tests and treatment.Öğe Clinical outcomes of trabeculectomy versus Ahmed glaucoma valve implantation in patients with penetrating keratoplasty(Springer, 2016) Ates, Halil; Palamar, Melis; Yagci, Ayse; Egrilmez, SaitÖğe Comparison of central corneal thickness and endothelial cell measurements by Scheimpflug camera system and two noncontact specular microscopes(Springer, 2018) Karaca, Irmak; Yilmaz, Suzan Guven; Palamar, Melis; Ates, HalilTo investigate the correlation of Scheimpflug camera system and two noncontact specular microscopes in terms of central corneal thickness (CCT) and corneal endothelial cell morphology measurements. One hundred eyes of 50 healthy subjects were examined by Pentacam Scheimpflug Analyzer, CEM-530 (Nidek Co, Ltd, Gamagori, Japan) and CellChek XL (Konan Medical, California, USA) via fully automated image analysis with no corrections made. Measurement differences and agreement between instruments were determined by intraclass correlation analysis. The mean age of the subjects was 36.74 +/- 8.59 (range 22-57). CCTs were well correlated among all devices, with having CEM-530 the thinnest and CellChek XL the thickest measurements (intraclass correlation coefficient (ICC) = 0.83; p < 0.001 and ICC = 0.78; p < 0.001, respectively). Mean endothelial cell density (ECD) given by CEM-530 was lower than CellChek XL (2613.17 +/- 228.62 and 2862.72 +/- 170.42 cells/mm(2), respectively; ICC = 0.43; p < 0.001). Mean value for coefficient of variation (CV) was 28.57 +/- 3.61 in CEM-530 and 30.30 +/- 3.53 in CellChek XL. Cell hexagonality (HEX) with CEM-530 was higher than with CellChek XL (68.70 +/- 4.16% and 45.19 +/- 6.58%, respectively). ECDs with CellChek XL and CEM-530 have good correlation, but the values obtained by CellChek XL are higher than CEM-530. Measurements for HEX and CV differ significantly and show weak correlation. Thus, we do not recommend interchangeable use of CellChek XL and CEM-530. In terms of CCTs, Pentacam, CEM-530 and CellChek XL specular microscopy instruments are reliable devices.Öğe Corneal Hysteresis, Corneal Resistance Factor, and Intraocular Pressure Measurement in Patients with Scleroderma Using the Reichert Ocular Response Analyzer(Lippincott Williams & Wilkins, 2010) Emre, Sinan; Kayikcioglu, Oezcan; Ates, Halil; Cinar, Esat; Inceoglu, Nehir; Yargucu, Figen; Pirildar, Timur; Oksel, FahrettinPurpose: The Reichert ocular response analyzer (ORA) measures corneal biomechanical properties in vivo by monitoring and analyzing the corneal behavior when its structure is submitted to a force induced by an air jet. This study was designed to examine corneal biomechanical properties and intraocular pressure in patients with systemic sclerosis (SSc) and to compare with control eyes. Patients and Methods: ORA measurements were performed on the right eyes of 29 patients with SSc (group 1) and 29 healthy people who served as the control group (group 2). Corneal hysteresis, conical resistance factor (CRF), and intraocular pressure [Goldmann correlated (IOPg) and conical compensated] were recorded with ORA. Results: Mean age of patients with SSc and control groups were 51.7 +/- 11.1 and 50.3 +/- 10.8 years, respectively. Mean (+/- SD) of the corneal hysteresis and CRF readings were 9.8 +/- 1.7 versus 9.5 +/- 1.2 mm Hg (P>0.05) and 10.0 +/- 1.5 versus 9.2 +/- 1.4 mm Hg (P<0.05), in groups 1 and 2, respectively. Mean (+/- SD) of the IOPg and intraocular pressure corneal-compensated recordings were 15.9 +/- 2.5 versus 14.1 +/- 2.4 mm Hg (P<0.05) and 16.9 +/- 3.2 versus 15.6 +/- 2.9 mm Hg (P>0.05), in groups 1 and 2, respectively. Statistical analysis revealed significant differences for CRF and IOPg between the study groups. Conclusions: The mean CRF and IOPg values of patients with SSc were higher when compared with normal controls. According to the results of our study, one can conclude that corneal biomechanical properties would be changed in patients with SSc and this can be determined by CRF.Öğe The Effect of Head Rotation on Intraocular Pressure in Prone Position: a Randomized Trial(Elsevier Science Inc, 2013) Deniz, M. Nuri; Erakgun, Arzum; Sertoz, Nezih; Yilmaz, Suzan Guven; Ates, Halil; Erhan, ElvanBackground and objectives: The increased intraocular pressure (IOP) - which decreases perfusion pressure on the optic nerve - increases by prone positioning (1). The aim of our study was to compare the effect of head rotation 45 degrees laterally in prone position on the increase in IOP of upper placed and lower placed eyes in patients undergoing percutaneous nephrolithotomy (PCNL). Methods: Forty-five patients were randomly divided into 2 Groups. IOP of the patients were recorded bilaterally in supine position before the operation had started. Patients were turned to prone position. The head was placed on a prone headrest without external direct compression to both eyes. Patients in Group I were kept in strictly neutral prone position where as patients in Group II were placed prone with their heads rotated 45 degrees laterally to the right side. At the end of the operation, patients were turned to supine position and their IOP was measured immediately. Results: There was no difference related to demographics, duration of surgery, blood loss and fluid input data. IOP values after surgery in prone position increased significantly compared to preoperative values in both groups (p < 0.05). After surgery in prone position IOP values of the upper positioned eyes in Group II were significantly lower than Group I and lower positioned eyes in Group II (p < 0.05). Conclusion: prone positioning increases IOP. In patients with prone position with a head rotation of 45 degrees laterally, IOP in the upper positioned eye was significantly lower. (C) 2013 Sociedade Brasileira de Anestesiologia. Published by Elsevier Editora Ltda. All rights reserved.Öğe The Effect of Head Rotation on Intraocular Pressure in Prone Position: a Randomized Trial(Elsevier Science Inc, 2013) Deniz, M. Nuri; Erakgun, Arzum; Sertoz, Nezih; Yilmaz, Suzan Guven; Ates, Halil; Erhan, ElvanBackground and objectives: The increased intraocular pressure (IOP) - which decreases perfusion pressure on the optic nerve - increases by prone positioning (1). The aim of our study was to compare the effect of head rotation 45 degrees laterally in prone position on the increase in IOP of upper placed and lower placed eyes in patients undergoing percutaneous nephrolithotomy (PCNL). Methods: Forty-five patients were randomly divided into 2 Groups. IOP of the patients were recorded bilaterally in supine position before the operation had started. Patients were turned to prone position. The head was placed on a prone headrest without external direct compression to both eyes. Patients in Group I were kept in strictly neutral prone position where as patients in Group II were placed prone with their heads rotated 45 degrees laterally to the right side. At the end of the operation, patients were turned to supine position and their IOP was measured immediately. Results: There was no difference related to demographics, duration of surgery, blood loss and fluid input data. IOP values after surgery in prone position increased significantly compared to preoperative values in both groups (p < 0.05). After surgery in prone position IOP values of the upper positioned eyes in Group II were significantly lower than Group I and lower positioned eyes in Group II (p < 0.05). Conclusion: prone positioning increases IOP. In patients with prone position with a head rotation of 45 degrees laterally, IOP in the upper positioned eye was significantly lower. (C) 2013 Sociedade Brasileira de Anestesiologia. Published by Elsevier Editora Ltda. All rights reserved.Öğe Effect of Tropicamide on Laser Flare Meter Measurements in Patients with Pseudoexfoliation(Taylor & Francis Inc, 2020) Karaca, Irmak; Yilmaz, Suzan Guven; Palamar, Melis; Ates, HalilPurpose: To investigate the effect of 1% tropicamide on anterior chamber aqueous flare (ACAF) measurements acquired with laser flare meter in patients with pseudoexfoliation. Methods: Thirty-three eyes of 33 patients with pseudoexfoliation were enrolled. Patients with the history of other ocular diseases, intraocular surgeries, and the presence of severe posterior synechia were excluded. Besides routine ophthalmological examination, ACAF levels were measured by laser flare meter device (Kowa FM 600) before and after instillation of 1% tropicamide. Results: The mean age of 33 patients was 67.3 +/- 7.1 (53-85) years. Patients had a mean best corrected visual acuity of 0.25 +/- 0.41 (1.80-0.00) logMAR, cup-to-disc ratio of 0.45 +/- 0.22 (0.2-1), and IOP of 15.33 +/- 2.82 (9-20) mmHg. Although the mean ACAF value increased from 14.68 +/- 8.40 (3.4-40.4) photon/ms predilation to 15.41 +/- 10.74 (3.8-46.8) photon/ms post-dilation, the difference was not statistically significant (p=0.835). Conclusions: ACAF values in patients with pseudoexfoliation did not significantly differ after instillation of 1% tropicamide.Öğe Effect of Tropicamide on Laser Flare Meter Measurements in Patients with Pseudoexfoliation(Taylor & Francis Inc, 2019) Karaca, Irmak; Yilmaz, Suzan Guven; Palamar, Melis; Ates, HalilPurpose: To investigate the effect of 1% tropicamide on anterior chamber aqueous flare (ACAF) measurements acquired with laser flare meter in patients with pseudoexfoliation. Methods: Thirty-three eyes of 33 patients with pseudoexfoliation were enrolled. Patients with the history of other ocular diseases, intraocular surgeries, and the presence of severe posterior synechia were excluded. Besides routine ophthalmological examination, ACAF levels were measured by laser flare meter device (Kowa FM 600) before and after instillation of 1% tropicamide. Results: The mean age of 33 patients was 67.3 +/- 7.1 (53-85) years. Patients had a mean best corrected visual acuity of 0.25 +/- 0.41 (1.80-0.00) logMAR, cup-to-disc ratio of 0.45 +/- 0.22 (0.2-1), and IOP of 15.33 +/- 2.82 (9-20) mmHg. Although the mean ACAF value increased from 14.68 +/- 8.40 (3.4-40.4) photon/ms predilation to 15.41 +/- 10.74 (3.8-46.8) photon/ms post-dilation, the difference was not statistically significant (p=0.835). Conclusions: ACAF values in patients with pseudoexfoliation did not significantly differ after instillation of 1% tropicamide.Öğe The effects of tropicamide and cyclopentolate hydrochloride on laser flare meter measurements in uveitis patients: a comparative study(Springer, 2021) Yilmaz, Medine; Yilmaz, Suzan Guven; Palamar, Melis; Ates, Halil; Yagci, AysePurposeTo investigate the effects of 1% cyclopentolate hydrochloride and 1% tropicamide eye drops on aqueous flare measurements by using the laser flare meter.MethodsOne hundred forty eight eyes of 83 patients with inactive uveitis were enrolled. The patients were randomly assigned to receive either 1% tropicamide (Group 1) or 1% cyclopentolate hydrochloride (Group 2) as the mydriatic agent. Best corrected visual acuity (BCVA), intraocular pressure (IOP), aqueous flare reaction levels measured by laser flare meter device (FM 600, Kowa, Kowa Company Ltd, Nagoya, Japan) before and post dilatation agents were evaluated.ResultsGroup 1 consisted of 75 eyes and Group 2 consisted of 77 eyes. The mean age of Group 1 patients was 34.8512.60 (range, 12-64) years; the mean age of Group 2 was 36.92 +/- 13.30 (range, 12-70) years (p>0.05). The mean BCVAs of two groups were 0.16 +/- 0.43 (range, 0.00-3.10) logMAR and 0.17 +/- 0.42 (range, 0.00-3.10) logMAR, respectively. There were no statistically significant differences between Groups 1 and 2 regarding gender or clinical characteristics (p>0.05). No significant differences were detected in pre- or post-dilatation values between two groups (p=0.470, p=0.998).Conclusions As a result, anterior chamber flare values in uveitis patients do not differ significantly between 1% tropicamide and 1% cyclopentolate hydrochloride, and both agents can be safely used for dilatation during examination of patients with uveitis.Öğe The efficacy and safety of bimatoprost/timolol maleate, latanoprost/timolol maleate, and travoprost/timolol maleate fixed combinations on 24-h IOP(Springer, 2018) Yilmaz, Suzan Guven; Degirmenci, Cumali; Karakoyun, Yunus Emre; Yusifov, Emil; Ates, HalilPurpose To evaluate the effect of bimatoprost/timolol maleate fixed combination (BTFC), latanoprost/timolol maleate fixed combination (LTFC), and travoprost/timolol maleate fixed combination (TTFC) on 24-h intraocular pressure (IOP) in patients with open-angle glaucoma. Methods This prospective, observer-masked, randomized study included 50 patients with primary open-angle glaucoma. All patients were using hypotensive lipids and timolol maleate fixed combination treatment for >= 4 weeks and had an IOP ae 21 mmHg. Group 1 (n = 18) received BTFC, group 2 (n = 14) received LTFC, and group 3 (n = 18) received TTFC. All patients were hospitalized, and IOP was monitored for 24-h (10:00, 14:00, 18:00, 22:00, 02:00, and 06:00). Mean diurnal IOP variation measurements were taken between 06:00 and 18:00, and mean nocturnal IOP variation measurements were taken between 22:00 and 02:00. Mean IOP and IOP variation in the three groups were compared. Results Mean 24-h IOP did not differ significantly between the three groups (group 1: 14.6 +/- 2.9 mmHg; group 2: 14.1 +/- 3.7 mmHg and group 3: 15.8 +/- 2.0 mmHg; P > 0.05). Mean diurnal IOP variation was 4.6 +/- 2.3 mmHg in group 1, 5.8 +/- 2.4 mmHg in group 2, and 4.3 +/- 1.7 mmHg in group 3, and mean nocturnal IOP variation was 3.2 +/- 2.8 mmHg in group 1, 2.9 +/- 1.9 mmHg in group 2, and 3.0 +/- 1.6 mmHg group 3. There were not any significant differences in diurnal or nocturnal IOP variation between the three groups (P < 0.05). Conclusion All three fixed combinations effectively controlled IOP for 24-h and had a similar effect on diurnal and nocturnal IOP variations.Öğe Evaluation of Ex-PRESS Mini Glaucoma Shunt Implantation in Refractory Postpenetrating Keratoplasty Glaucoma(Lippincott Williams & Wilkins, 2010) Ates, Halil; Palamar, Melis; Yagci, Ayse; Egrilmez, SaitPurpose: To evaluate the intraocular pressure (IOP) control and graft survival after Ex-PRESS mini glaucoma shunt implantation in refractory postpenetrating keratoplasty glaucoma. Methods: The study included postpenetrating keratoplasty glaucoma cases unresponsive to medical antiglaucomatous therapy in whom 15 Ex-PRESS mini glaucoma shunt implantation was carried out. All glaucoma shunt implantations were performed in a separate session after penetrating keratoplasty. Nine operations were performed under general anesthesia and 6 were performed under local anesthesia. Topical antibiotherapy and topical corticosteroids were used during the postoperative first month. Results: Mean age of the study population was 37.4 years (range: 10 to 80 y). IOP decreased from 41.46 mm Hg (range: 26 to 80 mm Hg) to 12.06 mm Hg (range: 8 to 25 mm Hg) over a mean follow-up of 12.2 months (range: 8 to 19 mo) (P<0.001; Wilcoxon signed rank test). IOP was below 21 mm Hg in 14 of 15 eyes (93.3%) with or without antiglaucomatous drugs. Complete success (IOP < 21 mm Hg without medication) rate was 86.6%. Average number of antiglaucomatous drug usage decreased from 3.20 (range: 2 to 4) preoperatively to 0.26 postoperatively (range: 0 to 3) (P < 0.001; Wilcoxon signed rank test). In 93.3% of the cases, the decrease in IOP was 30% or above postoperatively. After Ex-PRESS implantation, clear grafts remained clear while edematous grafts became clearer due to IOP decrease. Neither biomicroscopy nor pachymetry showed worsening of preoperatively opaque grafts. Conclusion: Ex-PRESS mini glaucoma shunt implantation may be an effective procedure for refractory postpenetrating keratoplasty glaucoma with acceptable graft failure rates in short term.Öğe Evaluation of Ex-PRESS mini glaucoma shunt implantation with preoperative intracameral bevacizumab injection in refractory neovascular glaucoma(Wichtig Publishing, 2016) Yilmaz, Suzan Guven; Yildirim, Seyda; Degirmenci, Cumali; Ates, HalilPurpose: To evaluate the efficacy and safety of Ex-PRESS mini glaucoma shunt implantation with preoperative intracameral bevacizumab injection in eyes with refractory neovascular glaucoma. Methods: A retrospective chart review of patients with medically uncontrolled neovascular glaucoma who had received 50-mu L intracameral bevacizumab (1.25 mg) before undergoing Ex-PRESS mini glaucoma shunt implantation was performed. Success was defined as a postoperative intraocular pressure (IOP) between 5 and 21 mm Hg without (complete success) or with or without (qualified success) glaucoma medications and no additional glaucoma surgery, or loss of light perception. Results: In total, 33 eyes of 33 patients (15 female, 18 male) were enrolled in the study. The mean age of the study population was 61.2 years (range 36-78). The mean IOP decreased from 41.0 mm Hg (range 24-72) to 17.6 mm Hg (range 8-28) over a mean follow-up of 20.9 months (range 6-60) (p<0.001; Wilcoxon signed-rank test). Complete and qualified success rates were 36.4% and 66.7%, respectively. The average number of antiglaucoma medications decreased from 3.5 (range 2-4) preoperatively to 1.8 (range 1-4) postoperatively (p<0.001; Wilcoxon signed rank test). In 81.8% of cases, the decrease in IOP was 30% or more postoperatively. Conclusions: Ex-PRESS mini glaucoma shunt implantation with preoperative bevacizumab injection may be an effective alternative procedure for refractory neovascular glaucoma.Öğe Evaluation of Ocular Surface and Meibomian Glands Alterations with Meibography in Patients with Inactive Behcet's Uveitis(Taylor & Francis Inc, 2019) Karaca, Irmak; Palamar, Melis; Yilmaz, Suzan Guven; Ates, HalilPurpose: To evaluate the ocular surface and meibography of patients with inactive Behcet's uveitis.Methods: Twenty-five right eyes of 25 patients with inactive Behcet's uveitis (Group 1) and 25 right eyes of 25 healthy individuals (Group 2) were enrolled. Detailed eye examination along with Schirmer 1 test, tear film break-up time (t-BUT), ocular surface staining with fluorescein and Oxford scoring, and ocular surface disease index (OSDI) score assessment were performed. Lower and upper eyelid Meibomian glands were examined with infrared filter of slit-lamp biomicroscope (SL-D701 with DC-4 digital camera and BG-5 background illuminator, TOPCON, Tokyo, Japan (from grade 0 (no dropout of Meibomian glands) to grade 3 (gland dropout >2/3 of the total Meibomian glands)).Results: The mean ages were 36.847.39 (range, 23-59) and 33.88 +/- 8.25 (range, 18-55) in Group 1 and Group 2, respectively (p =0.547). When compared with Group 2, in Group 1, best-corrected visual acuity (0.28 vs. 0.00 logMAR, p <0.001), Schirmer 1 test (18.68 vs. 23.69, p =0.017) and mean tear film break-up time (10.76 vs. 13.36, p =0.026) were significantly lower; Oxford scale and OSDI scores were higher (p =0.039 and p <0.001, respectively). No significant difference in lower, upper and total (upper + lower) meiboscores were detected in between groups (p =0.062, p =0.228 and p =0.152, respectively).Conclusion: Despite the tendency toward dry eye syndrome, Behcet's uveitis does not seem to be associated with quantitative Meibomian gland changes, which is demonstrated by gland drop-out with meibography.Öğe Evaluation of ocular surface and meibomian glands in patients with uveitis related to oligoarticular juvenile idiopathic arthritis(Springer, 2020) Degirmenci, Cumali; Palamar, Melis; Guven Yilmaz, Suzan; Ates, HalilPurpose To evaluate ocular surface changes and meibomian gland scores in patients with oligoarticular juvenile idiopathic arthritis. Materials and methods This prospective study was conducted at Ege University School of Medicine, Department of Ophthalmology. A total of 34 eyes of 17 patients with oligoarticular juvenile idiopathic arthritis and 30 right eyes of 30 age and gender-matched healthy subjects were included. Besides ophthalmic examination Schirmer 1 test, tear film break up time, Oxford staining scale and meibography were performed. Results There was no statistically significant differences between groups in terms of age, mean intraocular pressure, mean Schirmer 1 test value, tear film break up time and Oxford staining score. the median upper and lower eyelid meiboscore were 1 +/- 0.60 (IQR = 1), and 0 +/- 0.34 (IQR = 0) in Group 1, and they were 1 +/- 0.56 (IQR = 0), 1 +/- 0.12 (IQR = 1) in Group 2. Also, mean upper and lower meiboscores were statistically similar (pvalues 0.068 and 0.545, respectively). However, the median total meiboscore was 1 +/- 0.42 (IQR = 1) in Group 1 and 1 +/- 0.66 (IQR = 1) in Group 2. the difference was statistically significant (p = 0.041). Conclusion Aqueous-deficient dry eye is a well-known condition in patients with rheumatologic diseases. However, evaporative dry eye and meibomian glands were not studied earlier. the current study demonstrated that total meiboscores of oligoarticular juvenile idiopathic arthritis patients are higher than normal subjects, which indicates a possible evaporative dry eye tendency in this entity.Öğe Evaluation of the learning curve of non-penetrating glaucoma surgery(Springer, 2018) Aslan, Fatih; Yuce, Berna; Oztas, Zafer; Ates, HalilPurposeTo evaluate the learning curve of non-penetrating glaucoma surgery (NPGS).MethodsThe study included 32 eyes of 27 patients' (20 male and 7 female) with medically uncontrolled glaucoma. Non-penetrating glaucoma surgeries performed by trainees under control of an experienced surgeon between 2005 and 2007 at our tertiary referral hospital were evaluated. Residents were separated into two groups. Humanistic training model applied to the one in the first group, he studied with experimental models before performing NPGS. Two residents in the second group performed NPGS after a conventional training model. Surgeries of the residents were recorded on video and intraoperative parameters were scored by the experienced surgeon at the end of the study. Postoperative intraocular pressure, absolute and total success rates were analyzed.ResultsIn the first group 19 eyes of 16 patients and in the second group 13 eyes of 11 patients had been operated by residents. Intraoperative parameters and complication rates were not statistically significant between groups (p>0.05, Chi-square). The duration of surgery was 32.75.6min in the first group and 45 +/- 3.8min in the second group. The difference was statistically significant (p<0.001, Student's t test). Absolute and total success was 68.8 and 93.8% in the first group and 62.5 and 87.5% in the second group, respectively. The difference was not statistically significant.Conclusions Humanistic and conventional training models under control of an experienced surgeon are safe and effective for senior residents who manage phacoemulsification surgery in routine cataract cases. Senior residents can practice these surgical techniques with reasonable complication rates.Öğe Novel Ocular and Inner Ear Anomalies in a Patient with Myhre Syndrome(Karger, 2019) Gursoy, Semra; Hazan, Filiz; Ozturk, Tulay; Ates, HalilMyhre syndrome is a rare autosomal dominant multisystemic disorder. Typical features of this disorder include distinctive facial appearance, deafness, intellectual disability, cardiovascular abnormalities, short stature, brachydactyly, and skeletal anomalies. Gain-of-function mutations in the SMAD4 gene are responsible for this syndrome. Herein, we present a 9.6-year-old Turkish girl with molecularly confirmed Myhre syndrome who had novel findings including bilateral Axenfield Rieger anomaly with secondary glaucoma and bilateral enlarged vestibular aqueducts.Öğe Novel Ocular and Inner Ear Anomalies in a Patient with Myhre Syndrome(Karger, 2020) Gursoy, Semra; Hazan, Filiz; Ozturk, Tulay; Ates, HalilMyhre syndrome is a rare autosomal dominant multisystemic disorder. Typical features of this disorder include distinctive facial appearance, deafness, intellectual disability, cardiovascular abnormalities, short stature, brachydactyly, and skeletal anomalies. Gain-of-function mutations in the SMAD4 gene are responsible for this syndrome. Herein, we present a 9.6-year-old Turkish girl with molecularly confirmed Myhre syndrome who had novel findings including bilateral Axenfield Rieger anomaly with secondary glaucoma and bilateral enlarged vestibular aqueducts.Öğe Optic coherence tomography angiography findings in fuchs heterochromic iridocyclitis(Springer, 2022) Degirmenci, Cumali; Yarimada, Semir; Yilmaz, Suzan Guven; Nalcaci, Serhad; Ates, Halil; Afrashi, FilizPurpose To evaluate macular capillary perfusion in patients with fuchs heterochromic iridocyclitis (FHI) by using optical coherence tomography angiography (OCTA). Material and Method A total of 19 eyes of 19 patients with unilateral FHI underwent detailed eye examination. OCTA (RTVue-XR Avanti) images were obtained from both eyes. OCTA parameters, including foveal avascular zone, superficial capillary plexus and deep capillary plexus vessel densities, were compared between the involved and fellow control eyes. Results The median age of the patients (11 females, 8 males) was 42.0 +/- 9.63 (range 24-57) years. DCP and SCP densities at the parafoveal and perifoveal area were significantly lower in the FHI eyes compared to the control eyes (44.80 +/- 5.24% vs. 54.70 +/- 3.76% and 43.30 +/- 5.10% vs. 53.70 +/- 2.73%, respectively; p < 0.05). The median FAZ was 0.29 +/- 0.12 (0.11-0.42) mm(2) in the FHI eyes and 0.26 +/- 0.09 (0.10-0.40) mm(2) in the control eyes. This difference did not reach statistical significance (p = 0.199). Conclusion Macular capillary perfusion was significantly reduced in both SCP and DCP in the eyes with FHI. FHI, which is known to affect the choroid layer, could also compromise macular capillary perfusion of the retina.Öğe Optical coherence tomography angiography findings in Behcet patients(Springer, 2019) Emre, Sinan; Guven-Yilmaz, Suzan; Ulusoy, Mahmut Oguz; Ates, HalilPurposeRetinal vasculitis and vein occlusions are common causes of serious visual loss in Behcet's disease. We aimed to evaluate the optical coherence tomography angiography (OCTA) findings of Behcet uveitis (BU) patients.MethodsWe evaluated 32 eyes of 16 patients with BU and 30 eyes of 15 healthy controls. Superficial capillary plexus (SCP) and deeper capillary plexuses (DCP) were evaluated using OCTA RTVue XR AVANTI.ResultsOn SCP, nonperfusion/hypoperfusion areas (NPA) were seen in 10 eyes, perifoveal capillary arcade disruption (PCAD) was seen in 10 eyes, capillary network disorganization (CND) was seen in 7 eyes and intraretinal cystoid spaces (ICS) were seen in 2 eyes. on DCP, NPA were seen in 13 eyes, PCAD was seen in 11 eyes, CND was seen in 7 eyes and ICS were seen in 4 eyes.ConclusionWe showed that DCP were affected more than SCP in these patients. in addition, capillary vessel density of BU group was significantly lower than control group.Öğe Suprachoroidal implant surgery in intractable glaucoma(Springer Tokyo, 2011) Palamar, Melis; Ates, Halil; Oztas, Zafer; Yusifov, EmilTo report the early results of suprachoroidal silicone implant surgery in intractable glaucoma. A modified silicone implant with no valve was implanted into the suprachoroidal space of 15 eyes with intractable glaucoma. The mean age of the patients was 53.0 +/- A 24.5 (range 7-85) years, the mean follow-up time was 17.1 +/- A 4.8 (range 10-28) months, and the mean preoperative intraocular pressure (IOP) of patients receiving two or more medications was 33.1 +/- A 9.8 mmHg. At the last follow-up visit, mean IOP was 16.5 +/- A 7.9 (range 10-35) mmHg (Wilcoxon signed rank test, p = 0.001). The functional success, i.e., IOP a parts per thousand currency sign21 mmHg both with and without antiglaucomatous drugs, was 93.3%. The total success rate, i.e., IOP a parts per thousand currency sign21 mmHg without medication, was 13.3%. The average number of antiglaucomatous drugs used was 3.8 (range 2-5) preoperatively, and 2.2 postoperatively (range 0-4) (Wilcoxon signed rank test, p = 0.011). There was a a parts per thousand yen30% decrease in the IOP of 66.6% of the eyes. Shallow choroidal detachment as proof of drainage was evident in all cases. Drainage of the aqueous humor from the anterior chamber to the suprachoroidal space via implantation of a modified silicone implant is effective in lowering the IOP in intractable glaucoma.
