Effect of Tropicamide on Laser Flare Meter Measurements in Patients with Pseudoexfoliation

Purpose: To investigate the effect of 1% tropicamide on anterior chamber aqueous flare (ACAF) measurements acquired with laser flare meter in patients with pseudoexfoliation. Methods: Thirty-three eyes of 33 patients with pseudoexfoliation were enrolled. Patients with the history of other ocular diseases, intraocular surgeries, and the presence of severe posterior synechia were excluded. Besides routine ophthalmological examination, ACAF levels were measured by laser flare meter device (Kowa FM 600) before and after instillation of 1% tropicamide. Results: The mean age of 33 patients was 67.3 +/- 7.1 (53-85) years. Patients had a mean best corrected visual acuity of 0.25 +/- 0.41 (1.80-0.00) logMAR, cup-to-disc ratio of 0.45 +/- 0.22 (0.2-1), and IOP of 15.33 +/- 2.82 (9-20) mmHg. Although the mean ACAF value increased from 14.68 +/- 8.40 (3.4-40.4) photon/ms predilation to 15.41 +/- 10.74 (3.8-46.8) photon/ms post-dilation, the difference was not statistically significant (p=0.835). Conclusions: ACAF values in patients with pseudoexfoliation did not significantly differ after instillation of 1% tropicamide.