False negative high density lipoprotein-cholesterol in an autoimmune hepatitis patient: Case report [Otoimmün hepatitli bir olguda yanlis-negatif yüksek yogunluklu lipoprotein-kolesterol]

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dc.contributor.authorBarutçuoglu B.
dc.contributor.authorBaşol G.
dc.contributor.authorBozdemir A.E.
dc.contributor.authorKirdök S.
dc.contributor.authorHabif S.
dc.contributor.authorBayindir O.
dc.date.accessioned2019-10-26T22:47:21Z
dc.date.available2019-10-26T22:47:21Z
dc.date.issued2010
dc.departmentEge Üniversitesien_US
dc.description.abstractFalse-negative high density lipoprotein-cholesterol (HDL-C) detection is a remarkable condition in clinical laboratory practice. We report an 18-year-old female who admitted to transplantation division, with cirrhotic process of autoimmune hepatitis in which polyclonal hypergammaglobulinemia negatively interfered with HDL-C. The HDL-C and immunoglobulin G (IgG) levels were measured before and after liver transplantation. The patient had high IgG with polyclonal hypergammaglobulinemia and an undetectable HDL-C before transplantation. Falsely undetectable HDL-C levels were ruled out by two easy methods: sample dilution and back calculation based on Friedewald formula. This false negative value of HDL-C was also confirmed with lipoprotein electrophoresis. One must be careful in hyperimmunglobulinemic patients when using direct homogeneous HDL-C assay. © 2010 by Türkiye Klinikleri.en_US
dc.identifier.doi10.5336/medsci.2008-8234
dc.identifier.endpage398en_US
dc.identifier.issn1300-0292
dc.identifier.issn1300-0292en_US
dc.identifier.issue1en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage392en_US
dc.identifier.urihttps://doi.org/10.5336/medsci.2008-8234
dc.identifier.urihttps://hdl.handle.net/11454/20149
dc.identifier.volume30en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherTurkiye Kliniklerien_US
dc.relation.ispartofTurkiye Klinikleri Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAutoimmuneen_US
dc.subjectCholesterolen_US
dc.subjectHDLen_US
dc.subjectHepatitisen_US
dc.subjectHypergammaglobulinemiaen_US
dc.titleFalse negative high density lipoprotein-cholesterol in an autoimmune hepatitis patient: Case report [Otoimmün hepatitli bir olguda yanlis-negatif yüksek yogunluklu lipoprotein-kolesterol]en_US
dc.typeArticleen_US

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