Are COVID-19 vaccines safe for people with epilepsy? A cross-sectional study

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dc.authorscopusid57201367527
dc.authorscopusid57263915500
dc.authorscopusid6506799839
dc.authorscopusid6507032014
dc.contributor.authorOzdemir, Huseyin Nezih
dc.contributor.authorDere, Birgul
dc.contributor.authorGokcay, Figen
dc.contributor.authorGokcay, Ahmet
dc.date.accessioned2023-01-12T19:50:21Z
dc.date.available2023-01-12T19:50:21Z
dc.date.issued2022
dc.departmentN/A/Departmenten_US
dc.description.abstractBackground COVID-19 disease was first seen in December 2019 and was declared a pandemic soon after. To fight the pandemic, there is an immense need for effective vaccines. The purposes of our study were to investigate the effect of coronavirus vaccines on seizures in people with epilepsy (PWE) and assess the adverse events of COVID-19 vaccine in PWE. Methods This was a cross-sectional study. We included epilepsy patients who got vaccinated with two or three doses at least 1 month earlier. We gathered the data using a standardized form. The form contained questions about patients' demographic features, clinical features, and information about the vaccination and its adverse events. The questionnaire included questions about epilepsy-related adverse events. Results We included 178 people with epilepsy in our study. The frequency of adverse events was lower than clinical studies of the vaccines. The mean number of seizures in the month before the vaccination was 1.62, between the doses was 1.61, and after vaccination was 1.64. There was no significant difference in the number of monthly seizures before the vaccination, the month between the doses, or the month after the vaccination (p = 0.46). Conclusions The vaccines under consideration in our study were tolerated well by the epilepsy patients. The vaccines did not affect the monthly number of seizures of the PWE. A small number of patients had more seizures than normal after vaccination. We think that benefits of the vaccines outweigh the slightly increased possibility of having a seizure after vaccination.en_US
dc.identifier.doi10.1007/s10072-022-05956-6
dc.identifier.endpage3496en_US
dc.identifier.issn1590-1874
dc.identifier.issn1590-3478
dc.identifier.issue6en_US
dc.identifier.pmid35224704en_US
dc.identifier.scopus2-s2.0-85125418709en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage3489en_US
dc.identifier.urihttps://doi.org/10.1007/s10072-022-05956-6
dc.identifier.urihttps://hdl.handle.net/11454/76081
dc.identifier.volume43en_US
dc.identifier.wosWOS:000761734800001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer-Verlag Italia Srlen_US
dc.relation.ispartofNeurological Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectEpilepsyen_US
dc.subjectCOVID-19en_US
dc.subjectVaccineen_US
dc.subjectSafetyen_US
dc.subjectIlae Commissionen_US
dc.subjectSeizuresen_US
dc.titleAre COVID-19 vaccines safe for people with epilepsy? A cross-sectional studyen_US
dc.typeArticleen_US

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