Bruselloz Hastalarında Spondilodiskit ile İlişkili Faktörler
Küçük Resim Yok
Tarih
2016
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Giriş: Bruselloz birçok doku ve organı tutan, çok farklı klinik tablolarla ortaya çıkan bir sistemik infeksiyondur. Bu çalışmada, merkezimizde bruselloz spondilodiskiti tanısı takip edilen olguların irdelenmesi amaçlanmıştır. Materyal ve Metod: Bruselloz spondilodiskiti ile Temmuz 2007-Şubat 2016 tarihleri arasında kliniğimizde takip edilen olgular irdelendi. Bruselloz tanısı, mikrobiyolojik kültür ve/veya 1/160 titre ve üzeri aglütinasyon testi pozitifliği ile, spondilodiskit tanısı ise manyetik rezonans görüntüleme yöntemi ile konuldu. Veriler retrospektif yöntemle toplandı. Bulgular: Çalışma döneminde 94 bruselloz olgusu takip edildi (36 kadın, 58 erkek, yaş ortalaması 47.7 ± 15.5 yıl). Bu hastalardan 16 (%17)'sında spondilodiskit saptandı. Bu olguların ortalama yaşı 58.4 ± 11.1 yıl olup, spondilodiskit tespit edilmeyen olgulara (ortalama yaş 45.5 ± 15.4 yıl) göre anlamlı yüksek bulundu (p= 0.001). En sık tutulum görülen vertebralar alt torakal ve alt lomber vertebralardı. Bruselloz spondilodiskiti açısından yaş (p< 0.0001), ateş (p= 0.037), sırt ağrısı (p< 0.0001) ve halsizlik-yorgunluk (p= 0.012) anlamlı bulundu. Lojistik regresyon sonunda yaşın 54.5'ten büyük olması bruselloz spondilodiskiti için bağımsız risk faktörü olarak bulundu (OR= 9.12; %95 CI= 2.03-41.01; p= 0.004). Sonuç: Alt torakal ve alt lomber spondilodiskit olgularında bruselloz mutlaka taranmalıdır. Yaş bruselloz spondilodiskiti olgularında diğerlerine göre daha yüksek olup bruselloz spondilodiskiti için bağımsız risk faktörü olarak saptanmıştır
Introduction: Brucellosis is a systemic infection involving many organs and tissues which may present with very different clinical manifestations. In this study, it was aimed to review the cases with the diagnosis of brucellar spondylodiscitis followed up in our center. Materyal and Methods: Cases with the diagnosis of brucellar spondylodiscitis followed up in our clinic from July 2007 to February 2016 were reviewed. Brucellosis diagnosis was established via microbiological culture confirmation and/or agglutination test positivity with a titer of 1/160 or higher. The diagnosis of spondylodiscitis was made with magnetic resonance imaging method. The data were collected by retrospective chart review. Results: During the study period, 94 cases of brucellosis were followed (36 females, 58 males, mean age:47.7 ± 15.5 years). Spondylodiscitis was detected in 16 (17%) patients. The mean age of this group was 58.4 ± 11.1 and it was detected to be significantly higher than patients without spondylodiscitis (mean age 45.5 ± 15.4 years) (p= 0.001). The most frequently involved vertebrae were the lower thoracic and lower lumbar vertebras. Age (p< 0.0001), fever (p= 0.037), backache (p< 0.0001) and weakness-fatigue (p= 0.012) were found statically significant factors for spondylodiscitis. At the end of logistic regression, age higher than 54.5 years was found to be an independent risk factor of the brucellar spondylodiscitis (OR= 9.12; %95 CI= 2.03-41.01; p= 0.004). Conclusion: Brucellosis should be screened in cases with lower thoracic and lower lumbar spondylodiscitis. Age is higher in patients with brucellar spondylodiscitis than others and age > 54.5 years is an independent risk factor for brcsellar spondylodiscitis.
Introduction: Brucellosis is a systemic infection involving many organs and tissues which may present with very different clinical manifestations. In this study, it was aimed to review the cases with the diagnosis of brucellar spondylodiscitis followed up in our center. Materyal and Methods: Cases with the diagnosis of brucellar spondylodiscitis followed up in our clinic from July 2007 to February 2016 were reviewed. Brucellosis diagnosis was established via microbiological culture confirmation and/or agglutination test positivity with a titer of 1/160 or higher. The diagnosis of spondylodiscitis was made with magnetic resonance imaging method. The data were collected by retrospective chart review. Results: During the study period, 94 cases of brucellosis were followed (36 females, 58 males, mean age:47.7 ± 15.5 years). Spondylodiscitis was detected in 16 (17%) patients. The mean age of this group was 58.4 ± 11.1 and it was detected to be significantly higher than patients without spondylodiscitis (mean age 45.5 ± 15.4 years) (p= 0.001). The most frequently involved vertebrae were the lower thoracic and lower lumbar vertebras. Age (p< 0.0001), fever (p= 0.037), backache (p< 0.0001) and weakness-fatigue (p= 0.012) were found statically significant factors for spondylodiscitis. At the end of logistic regression, age higher than 54.5 years was found to be an independent risk factor of the brucellar spondylodiscitis (OR= 9.12; %95 CI= 2.03-41.01; p= 0.004). Conclusion: Brucellosis should be screened in cases with lower thoracic and lower lumbar spondylodiscitis. Age is higher in patients with brucellar spondylodiscitis than others and age > 54.5 years is an independent risk factor for brcsellar spondylodiscitis.
Açıklama
Anahtar Kelimeler
Mikrobiyoloji, Enfeksiyon Hastalıkları
Kaynak
Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
21
Sayı
2
