A Rare Cause of Metabolic Acidosis

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dc.contributor.authorSahbudak Bal Z.
dc.contributor.authorCan F.K.
dc.contributor.authorAnil A.B.
dc.contributor.authorBal A.
dc.contributor.authorAnil M.
dc.contributor.authorGokalp G.
dc.contributor.authorYavascan O.
dc.contributor.authorAksu N.
dc.date.accessioned2019-10-26T21:18:18Z
dc.date.available2019-10-26T21:18:18Z
dc.date.issued2016
dc.departmentEge Üniversitesien_US
dc.description.abstractOral methanol intoxication is common, but dermal intoxication is rare. We report a previously healthy 19-month-old female infant admitted to the emergency department (ED) with vomiting and tonic-clonic seizure. On physical examination, she was comatose and presented signs of decompensated shock with Kussmaul breathing. Her left thigh was edematous, with purple coloration. Methanol intoxication was suspected due to high anion gap metabolic acidosis (pH, 6.89; HCO 3, <3 meq/L) and exposure to spirit-soaked bandages (%96 methanol) for 24 hours and 3 days. The patient's serum methanol level was 20.4 mg/dL. She was treated with fomepizole and continuous venovenous hemodialysis (CVVHD) in the pediatric intensive care unit, and methanol levels decreased to 0 mg/dL after 12 hours. During follow-up, massive edema and subarachnoid hemorrhage in the occipital lobe were detected by computed tomography of the brain. The patient died after 7 days. Although methanol intoxication occurs predominantly in adults, it must be considered in children with high-anion gap metabolic acidosis. This case report demonstrates that fatal transdermal methanol intoxication can occur in children, and it is the second report in the English literature of transdermal methanol intoxication in an infant. © 2015 Wolters Kluwer Health, Inc. All rights reserved.en_US
dc.identifier.doi10.1097/PEC.0000000000000478en_US
dc.identifier.endpage533en_US
dc.identifier.issn0749-5161
dc.identifier.issue8en_US
dc.identifier.pmid26196361en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage532en_US
dc.identifier.urihttps://doi.org/10.1097/PEC.0000000000000478
dc.identifier.urihttps://hdl.handle.net/11454/16497
dc.identifier.volume32en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams and Wilkinsen_US
dc.relation.ispartofPediatric Emergency Careen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectmetabolic acidosisen_US
dc.subjecttransdermal methanol intoxicationen_US
dc.titleA Rare Cause of Metabolic Acidosisen_US
dc.typeArticleen_US

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