Effect of fluconazole prophylaxis on fungal colonisation in ICU patients

dc.contributor.authorMoral A.R.
dc.contributor.authorTumbay E.
dc.contributor.authorUlusoy B.
dc.contributor.authorAksoy N.
dc.contributor.authorCevik A.
dc.contributor.authorInci R.
dc.date.accessioned2019-10-27T00:33:24Z
dc.date.available2019-10-27T00:33:24Z
dc.date.issued1994
dc.departmentEge Üniversitesien_US
dc.description.abstractIn this study, the effect of fluconazole prophylaxis on the incidence of fungal (yeast) colonization in multidisciplinary ICU patients were investigated. A total of 252 patients were mycologically screened in the first week of their hospitalization and followingly once every week. The specimens studied were blood (from venous route and from central venous catheter) urine catheter, endotracheal tubes, oral cavity, nares, skin and rectal swabs. The fungus isolated was candida. 91 received fluconazole 100 mg/day IV or enterally for prophylaxis and 161 served as the control group. Total number of samples in study was 2852 and 1723 of these samples were from the control group, 27.5% being positive. 1129 samples were taken from the prophylaxis group while 18.8% were positive. In conclusion, prophylactic treatment with 100 mg/day fluconazole significantly decreases the incidence of fungal colonization in ICU patients (p<0.01).en_US
dc.identifier.endpage240en_US
dc.identifier.issn1016-5150
dc.identifier.issn1016-5150en_US
dc.identifier.issue5en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage236en_US
dc.identifier.urihttps://hdl.handle.net/11454/24047
dc.identifier.volume22en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.relation.ispartofTurk Anesteziyoloji ve Reanimasyonen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCandida colonizationen_US
dc.subjectFluconazoleen_US
dc.subjectMultidisciplinary ICUen_US
dc.titleEffect of fluconazole prophylaxis on fungal colonisation in ICU patientsen_US
dc.typeArticleen_US

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