Effect of fluconazole prophylaxis on fungal colonisation in ICU patients
Küçük Resim Yok
Tarih
1994
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In this study, the effect of fluconazole prophylaxis on the incidence of fungal (yeast) colonization in multidisciplinary ICU patients were investigated. A total of 252 patients were mycologically screened in the first week of their hospitalization and followingly once every week. The specimens studied were blood (from venous route and from central venous catheter) urine catheter, endotracheal tubes, oral cavity, nares, skin and rectal swabs. The fungus isolated was candida. 91 received fluconazole 100 mg/day IV or enterally for prophylaxis and 161 served as the control group. Total number of samples in study was 2852 and 1723 of these samples were from the control group, 27.5% being positive. 1129 samples were taken from the prophylaxis group while 18.8% were positive. In conclusion, prophylactic treatment with 100 mg/day fluconazole significantly decreases the incidence of fungal colonization in ICU patients (p<0.01).
Açıklama
Anahtar Kelimeler
Candida colonization, Fluconazole, Multidisciplinary ICU
Kaynak
Turk Anesteziyoloji ve Reanimasyon
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
22
Sayı
5
