Genetic characterization of Bartonella henselae samples isolated from stray cats by multi-locus sequence typing

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dc.authorscopusid23003351400
dc.authorscopusid57221117593
dc.authorscopusid57216298658
dc.authorscopusid25825299300
dc.authorscopusid57212213434
dc.authorscopusid56495590200
dc.authorscopusid57219922088
dc.contributor.authorCan, H.
dc.contributor.authorGüvendi, M.
dc.contributor.authorSürgeç, E.
dc.contributor.authorKöseoğlu, A.E.
dc.contributor.authorErkunt, Alak, S.
dc.contributor.authorKarakavuk, M.
dc.contributor.authorGül, A.
dc.date.accessioned2024-08-25T18:47:41Z
dc.date.available2024-08-25T18:47:41Z
dc.date.issued2023
dc.departmentEge Üniversitesien_US
dc.description.abstractBackground: Bartonella henselae is one of the most commonly identified Bartonella species associated with several human diseases. Although B. henselae was detected in humans and cats in Turkey, they have not been genotyped previously. Therefore, this study aimed to genotype B. henselae samples (n = 44) isolated from stray cats using the multi-locus sequence typing (MLST) method. For this aim, eight different housekeeping markers were amplified by nested PCR and then sequenced to reveal sequence types (STs) of B. henselae samples. Results: Allelic profiles obtained from 40 B. henselae isolates (90.9%) were compatible with available allelic profiles in the MLST online database. However, allelic profiles obtained from the remaining 4 B. henselae isolates (9.1%) were incompatible with the database. Among B. henselae isolates with compatible allelic profiles, 5 different STs including ST1, ST5, ST9, ST35 and ST36 were identified according to the B. henselae MLST online database. ST35 was the most prevalent ST with a prevalence rate of 29.5% (13/44), followed by ST36 with a prevalence rate of 22.7% (10/44). In addition, ST5 (16%, 7/44) and ST9 (18.2%, 8/44) were also among the prevalent STs. The prevalence of ST1 was 4.5% (2/44). For B. henselae isolates with incompatible allelic profiles, we recommended a new ST called ST38. Conclusion: The present study genotyped B. henselae samples isolated from stray cats in Turkey for the first time and ST1, ST5, ST9, ST35, and ST36 as well as a new sequence type named ST38 were identified among these B. henselae isolates. © 2023, BioMed Central Ltd., part of Springer Nature.en_US
dc.description.sponsorshipEge Üniversitesi: TGA-2022-23254en_US
dc.description.sponsorshipThis study was supported by a project given by the Ege University Scientific Research Projects Coordination Unit (Project number: TGA-2022-23254) to H.C.en_US
dc.identifier.doi10.1186/s12917-023-03748-4
dc.identifier.issn1746-6148
dc.identifier.issue1en_US
dc.identifier.pmid37805521en_US
dc.identifier.scopus2-s2.0-85173954313en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1186/s12917-023-03748-4
dc.identifier.urihttps://hdl.handle.net/11454/102009
dc.identifier.volume19en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBioMed Central Ltden_US
dc.relation.ispartofBMC Veterinary Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240825_Gen_US
dc.subjectB. henselaeen_US
dc.subjectGenetic diversityen_US
dc.subjectGenotypingen_US
dc.subjectNew sequence typeen_US
dc.titleGenetic characterization of Bartonella henselae samples isolated from stray cats by multi-locus sequence typingen_US
dc.typeArticleen_US

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