Reproductive and Sexual Functions in Bipolar Patients: Data from a Specialized Mood Disorder Clinic

dc.contributor.authorAldemir, Ebru
dc.contributor.authorAkdeniz, Fisun
dc.contributor.authorIsikli, Serhan
dc.contributor.authorBilen, Nesli Keskinoz
dc.contributor.authorVahip, Simavi
dc.date.accessioned2019-10-27T23:10:51Z
dc.date.available2019-10-27T23:10:51Z
dc.date.issued2016
dc.departmentEge Üniversitesien_US
dc.description.abstractObjective: The objective of this study is to investigate the reproductive characteristics and sexual functions in bipolar patients monitored in a specialized mood disorder clinic, identify their potential relationship with the use of psychotropics, and investigate gender differences. Method: The study included 193 patients (100 men, 93 women) with a DSM-IV diagnosis of bipolar disorder being followed at Ege University Affective Disorders Outpatient Unit. Reproductive characteristics of the patients were examined at the evaluation. Sexual dysfunctions were evaluated using the International Index of Erectile Function in men and Arizona Sexual Experience Scale in women. Results: There was no significant difference between men and women regarding age, duration of marriage, duration of illness, duration of mood stabilizer and antipsychotic drugs use and dosage of antipsychotic drugs. Age at pubarche in men was 13.8 +/- 1.2 years, age at menarche in women was 13.2 +/- 1.3 years. Current menstrual cycle irregularities were found in 15.1% (n=14) of women. Prevalence of lifetime menstrual irregularities was 38.7% (n=36). 60.4% (n=67) of patients having an active sexual life were using an effective contraception method. 31.7% (n=26) of female patients had sexual dysfunction whilst 52% (n=39) of male patients had erectile dysfunction. In both men and women, no significant difference was found between groups using mood stabilizers and antipsychotic drugs in terms of sexual dysfunction. There was no correlation between sexual function scores and usage and duration of mood stabilizers and antipsychotic drugs in either sex. Conclusions: This cross-sectional study with a relatively large bipolar sample group concluded that the patients' reproductive and sexual functions were not as much affected by bipolar disorder and psychotropic drug use as had been assumed. However, these results should be supported with prospective and controlled trials.en_US
dc.identifier.doi10.5350/DAJPN2016290107
dc.identifier.endpage75en_US
dc.identifier.issn1018-8681
dc.identifier.issn1309-5749
dc.identifier.issue1en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage67en_US
dc.identifier.urihttps://doi.org/10.5350/DAJPN2016290107
dc.identifier.urihttps://hdl.handle.net/11454/52972
dc.identifier.volume29en_US
dc.identifier.wosWOS:000383250200007en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherYerkure Tanitim & Yayincilik Hizmetleri A Sen_US
dc.relation.ispartofDusunen Adam-Journal of Psychiatry and Neurological Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBipolar disorderen_US
dc.subjectreproductive functionsen_US
dc.subjectsexual functionsen_US
dc.titleReproductive and Sexual Functions in Bipolar Patients: Data from a Specialized Mood Disorder Clinicen_US
dc.typeArticleen_US

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