Chlamydia pneumoniae arthritis in a patient with common variable immunodeficiency

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dc.contributor.authorArdeniz, O
dc.contributor.authorGulbahar, O
dc.contributor.authorMete, N
dc.contributor.authorCicek, C
dc.contributor.authorBasoglu, OK
dc.contributor.authorSin, A
dc.contributor.authorKokuludag, A
dc.date.accessioned2019-10-27T18:58:22Z
dc.date.available2019-10-27T18:58:22Z
dc.date.issued2005
dc.departmentEge Üniversitesien_US
dc.description.abstractBackground: Arthritis is an important and sometimes life-threatening complication in patients with common variable immunodeficiency (CVID). Objective: To describe a patient with CVID and arthritis due to Chlamydia pneumoniae, which is usually regarded as a respiratory tract pathogen and has not previously been detected in the synovial fluid by cell culture technique. Methods: Routine bacteriologic, virologic, mycologic, and tuberculosis cultures were performed. The patient's synovial fluid was examined for fastidious organisms that might be causative pathogens of arthritis, such as chlamydiae, and special cell culture methods were used. Serologic tests were performed to determine viral and bacteriologic etiology. Results: The patient had a history of recurrent respiratory tract infections, and the latest exacerbation was followed by arthritis. Cytologic examination of the fluid yielded abundant lymphocytes. Chlamydia pneumoniae was detected in synovial fluid specimens by cell culture technique. Her nasopharyngeal swab and sputum culture specimens were also positive for this pathogen. She was diagnosed as having arthritis caused by C pneumoniae and was given antibiotherapy. Conclusion: Chlamydia pneumoniae should be kept in mind as a causative pathogen in patients with CVID and arthritis, especially when effusion fluid is full of lymphocytes rather than polymorphonuclear cells and no organism is grown on routine cultures.en_US
dc.identifier.doi10.1016/S1081-1206(10)61122-2en_US
dc.identifier.endpage508en_US
dc.identifier.issn1081-1206
dc.identifier.issue4en_US
dc.identifier.pmid15875533en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage504en_US
dc.identifier.urihttps://doi.org/10.1016/S1081-1206(10)61122-2
dc.identifier.urihttps://hdl.handle.net/11454/37468
dc.identifier.volume94en_US
dc.identifier.wosWOS:000228578300013en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAmer Coll Allergy Asthma Immunologyen_US
dc.relation.ispartofAnnals of Allergy Asthma & Immunologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleChlamydia pneumoniae arthritis in a patient with common variable immunodeficiencyen_US
dc.typeArticleen_US

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