Fine Needle Aspiration Cytologic Features of Medullary Carcinoma of the Breast A Study of 20 Cases with Histologic Correlation

Basit Öğe Kaydı
dc.contributor.authorAkbulut, Metin
dc.contributor.authorZekioglu, Osman
dc.contributor.authorKapkac, Murat
dc.contributor.authorOzdemir, Necmettin
dc.date.accessioned2019-10-27T20:19:05Z
dc.date.available2019-10-27T20:19:05Z
dc.date.issued2009
dc.departmentEge Üniversitesien_US
dc.description.abstractObjective To analyze fine needle aspiration cytology (FNAC) mater material from 20 cases of histologically verified medullary carcinoma (MC) of the breast and correlate the cytomorphologic features with histologic appearance to improve the diagnostic sensitivity and specificity of FNAC. Study Design We reviewed the cytologic features of 20 cases of MC of the breast in the archives of Ege University Hospital between 1994 and 2006. Results Twenty patients with an aspirate and confirmed diagnosis of MC were identified. Patient age was 30-74 years (mean, 48). The initial cytologic diagnoses were positive for cancer in 17 cases, atypical/suspicious for cancer in 2 cases and negative for cancer in 1 case. The cytologic picture was characterized by cellular smears composed of highly atypical epithelial tumor cells in loosely cohesive sheets and lying singly, admixed with polymorphous lymphocytes, plasma cells and neutrophils. Tumor cells had predominantly abundant finely granular, eosinophilic cytoplasm and moderate to marked nuclear pleomorphism with prominent nucleoli. Histologic examination confirmed that 11 cases were atypical MC and 9 were pure MC. Conclusion Breast MC is a rare, distinct category that appears to have rather characteristic cellular features. Familiarity with the cell components is a prerequisite in cytologic accuracy. (Acta Cytol 2009;53:165173)en_US
dc.identifier.endpage173en_US
dc.identifier.issn0001-5547
dc.identifier.issn1938-2650
dc.identifier.issue2en_US
dc.identifier.pmid19365969en_US
dc.identifier.startpage165en_US
dc.identifier.urihttps://hdl.handle.net/11454/41315
dc.identifier.volume53en_US
dc.identifier.wosWOS:000264304100008en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKargeren_US
dc.relation.ispartofActa Cytologicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectbreasten_US
dc.subjectcytologyen_US
dc.subjectmedullary carcinomaen_US
dc.titleFine Needle Aspiration Cytologic Features of Medullary Carcinoma of the Breast A Study of 20 Cases with Histologic Correlationen_US
dc.typeArticleen_US

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