Benzimidazole-Platinum Complex and Its Cytotoxic activity on U87 Cell Lines

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Tarih

2024

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

The aim of the study is to evaluate the synthesis, characterization and cytotoxic activities of a novel benzimidazole-platinum(II) complex that may have strong cytotoxic activity and low side effects. A benzimidazole ligand, 2-(3-phenoxyphenyl)-1-phenyl-1H-benzimidazole (L) and its novel platinum complex (Pt-L) was synthesized and characterized by different spectroscopic methods. In the study, firstly the activity of the synthesized complex in the U87 cancer line was examined and then it has been studied on healthy Vero lines.

Açıklama

Anahtar Kelimeler

Benzimidazole, Benzimidazole- Platinum complexes, glioblastoma, cytotoxic activity

Kaynak

Erzincan Üniversitesi Fen Bilimleri Enstitüsü Dergisi

WoS Q Değeri

Scopus Q Değeri

Cilt

17

Sayı

1

Künye