Determination and Comparison of in Vitro Radical Scavenging Activity of Both Garlic Oil and Aqueous Garlic Extracts and Their in Vivo Antioxidant Effect on Schistosomiasis Disease in Mice

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dc.contributor.authorSadrefozalayi, Somayyeh
dc.contributor.authorAslanipour, Behnaz
dc.contributor.authorAlan, Murat
dc.contributor.authorÇalan, Mehmet
dc.date.accessioned2020-12-01T12:33:02Z
dc.date.available2020-12-01T12:33:02Z
dc.date.issued2018
dc.departmentEge Üniversitesien_US
dc.description.abstractGarlic has long been utilizing as a folk remedy for various diseases. in this study, the effect of aqueous garlic extract (AGE) (125 mg kg-1), garlic oil extract (GOE) (125 mg kg-1), and the combination of both extracts (AGE+GOE) (62.5 from each) was studied over a parasitic disease namely schistosomiasis. Determination of some radical scavenging activities including Ferric Reducing Ability Power, Hydrogen peroxide, DPPH and nitric oxide radical scavenging activities were studied. the antioxidant properties of the mentioned extracts on both normal and Schistosoma mansoni-infected mice was also studied. the liver tissues were analyzed for the level of Malondialdehyde (MDA) and glutathione (GSH) known as biomarkers for oxidative and reducing status, respectively. the results showed that almost all tested extracts showed high effect of radical scavenging activity. Furthermore, remarkable decrease in worms and tissue eggs were analyzed in all tested extracts as AGE+ GOE (1015 ± 1.41) represented higher level of prohibition in total number of worms and eggs compared to infected untreated mice (1502 ± 2.13). the garlic extracts were potent antioxidants with slight differences.en_US
dc.identifier.endpage827en_US
dc.identifier.issn2148-127X
dc.identifier.issn2148-127X
dc.identifier.issue7en_US
dc.identifier.startpage820en_US
dc.identifier.urihttps://app.trdizin.gov.tr//makale/TXpJek1UUXdNQT09
dc.identifier.urihttps://hdl.handle.net/11454/66432
dc.identifier.volume6en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofTürk Tarım - Gıda Bilim ve Teknoloji dergisien_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectZiraat Mühendisliğien_US
dc.subjectGıda Bilimi ve Teknolojisien_US
dc.titleDetermination and Comparison of in Vitro Radical Scavenging Activity of Both Garlic Oil and Aqueous Garlic Extracts and Their in Vivo Antioxidant Effect on Schistosomiasis Disease in Miceen_US
dc.typeArticleen_US

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