Role of vascularization in determining the time of hypoxic-ischemic encephalopathy in the neonate

Basit Öğe Kaydı
dc.contributor.authorAktas, EO
dc.contributor.authorAktas, S
dc.contributor.authorOrtac, R
dc.contributor.authorDiniz, G
dc.date.accessioned2019-10-27T18:39:18Z
dc.date.available2019-10-27T18:39:18Z
dc.date.issued2003
dc.departmentEge Üniversitesien_US
dc.description.abstractOBJECTIVE: To examine the role of vascularization in determining the time of hypoxic-ischemic encephalopathy (HIEP). STUDY DESIGN: Brain sections of 126 neonatal autopsy cases were examined for edema, gliosis, congestion, inflammation and ischemia. Capillary vessels were examined with both reticulum stains and antibody against CD34. Vascular surface density (VSD) and number of vessels per stroma (NVES) were calculated by stereologic methods. RESULTS: Among 126 cases, 64 were male (50.8%) and 62 female (49.2%). In 25 cases HIEP was observed; 14 had a pregnancy history of hypertension, eclampsia or diabetes mellitus in the mother, with fetal distress or underdeveloped features. Statistically, NVES was strongly related to primary HIEP. However, the HIEP and non-HIEP cases revealed no differences in NVES and VSD means. CONCLUSION: Vascularization, especially NVES, helps in determining whether an HIEP case is pregnancy related or due to end-stage changes of dying, but is not an indicator of HIEP.en_US
dc.identifier.endpage180en_US
dc.identifier.issn0884-6812
dc.identifier.issue3en_US
dc.identifier.pmid12882089en_US
dc.identifier.startpage177en_US
dc.identifier.urihttps://hdl.handle.net/11454/36746
dc.identifier.volume25en_US
dc.identifier.wosWOS:000183498200007en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSci Printers & Publ Incen_US
dc.relation.ispartofAnalytical and Quantitative Cytology and Histologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectblood vesselsen_US
dc.subjecthypoxic-ischemic encephalopathyen_US
dc.subjectneonateen_US
dc.subjectvascularizationen_US
dc.titleRole of vascularization in determining the time of hypoxic-ischemic encephalopathy in the neonateen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu