Evaluation of Growth After Liver Transplantation in Turkish Children

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dc.contributor.authorBaran, Masallah
dc.contributor.authorCakir, Murat
dc.contributor.authorUnal, Fatih
dc.contributor.authorTumgor, Gokhan
dc.contributor.authorYuksekkaya, Hasan Ali
dc.contributor.authorArikan, Cigdem
dc.contributor.authorKilic, Murat
dc.contributor.authorAydogdu, Sema
dc.date.accessioned2019-10-27T21:35:33Z
dc.date.available2019-10-27T21:35:33Z
dc.date.issued2011
dc.departmentEge Üniversitesien_US
dc.description.abstractAims Currently, the main interest in childhood liver transplantation (LT) is to prevent long-term complications and optimize growth. The aim of this study is to analyze (1) nutritional status in the pretransplantation period, and (2) posttransplantation growth and associated factors in children. Patients and Methods Eighty children were included in the study. Height (Z (H)) and weight (Z (W)) Z scores were calculated before transplantation and postoperatively at the 6th month and 1st, 2nd, 3rd, 4th, and 5th year. Results Patients' Z (H) and Z (W) scores at LT were -1.6 +/- A 1.3 and -1.5 +/- A 1.4, respectively. Both Z (H) and Z (W) scores increased after LT, especially in the first 6 months, and then continued to rise gradually. Both reached beyond -1 Z score at 2nd year and -0.5 at 4th year. Age, primary diagnosis, total steroid dose (< 1,000 mg), and absence of rejection episodes had positive impact on posttransplantation growth, whereas gender, immunosuppression type, surgical complications, and presence of tumor had no impact on posttransplantation growth. Age at time of LT was negatively correlated with Z (W) score at 5th year (P = 0.02, r = -0.43). Both Z (W) and Z (H) scores at time of LT were positively correlated with Z (W) and Z (H) scores and negatively correlated with a dagger Z (W) and a dagger Z (H) scores at 5th year. Conclusions LT is not only a modern, life-saving treatment technique but also an efficient method of facilitating growth, an indispensable component of childhood and the best indicator of health.en_US
dc.identifier.doi10.1007/s10620-011-1727-6en_US
dc.identifier.endpage3349en_US
dc.identifier.issn0163-2116
dc.identifier.issue11en_US
dc.identifier.pmid21562786en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage3343en_US
dc.identifier.urihttps://doi.org/10.1007/s10620-011-1727-6
dc.identifier.urihttps://hdl.handle.net/11454/45884
dc.identifier.volume56en_US
dc.identifier.wosWOS:000296643400033en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofDigestive Diseases and Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLiver transplantationen_US
dc.subjectChildrenen_US
dc.subjectGrowthen_US
dc.titleEvaluation of Growth After Liver Transplantation in Turkish Childrenen_US
dc.typeArticleen_US

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