The first report in Turkey of in vivo cultivation in Rattus norvegicus of Echinococcus multilocularis human strain
Küçük Resim Yok
Tarih
2007
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Echinococcus multilocularis'in erişkin formu, tilkiler başta olmak üzere etçillerde bulunan küçük bir sestoddur. Dünyanın Kuzey Yarımküresinde görülen bu sestod insanlarda genellikle ölümcül seyreden bir hastalık olan alveolar echinococcosisin etkenidir. Echinococcus multilocularis metasestodları Rattus norvegicus (sıçan) türü kemirgenlerde deneysel olarak geliştirilebilmekte, elde edilen metasestodlardan başta tanı için gerekli antijenler olmak üzere çok amaçlı yararlanılabilmektedir. Bu amaçla, Echinococcus multilocularis ile enfekte insandan alınan materyal, farklı bir kemirgen türü olan Rattus norvegicus (sıçan)'a inokule edilerek Echinococcus multilocularis suşu izole edilmiştir.
The adult form of the small cestode Echinococcus multilocularis is found in carnivorous animals, especially in the fox. This cestode, which is found in the northern hemisphere in the world, is the cause of a generally fatal disease in humans, known as alveolar echinococcosis (AE). The metacestodes of Echinococcus multilocularis can be experimentally developed in the Meriones unguiculatus species of rodents, and it is possible to use these metacestodes for numerous purposes, primarily for supplying the antigens required for serological diagnosis of the disease. It is with this aim that in this study for the first time in Turkey, Echinococcus multilocularis metacestodes were developed using different kind of rodent, Rattus norvegicus, and an indigenous strain was isolated using the surgical material of a patient diagnosed with alveolar echinococcosis.
The adult form of the small cestode Echinococcus multilocularis is found in carnivorous animals, especially in the fox. This cestode, which is found in the northern hemisphere in the world, is the cause of a generally fatal disease in humans, known as alveolar echinococcosis (AE). The metacestodes of Echinococcus multilocularis can be experimentally developed in the Meriones unguiculatus species of rodents, and it is possible to use these metacestodes for numerous purposes, primarily for supplying the antigens required for serological diagnosis of the disease. It is with this aim that in this study for the first time in Turkey, Echinococcus multilocularis metacestodes were developed using different kind of rodent, Rattus norvegicus, and an indigenous strain was isolated using the surgical material of a patient diagnosed with alveolar echinococcosis.
Açıklama
Anahtar Kelimeler
Parazitoloji, Genel ve Dahili Tıp
Kaynak
Türkiye Parazitoloji Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
31
Sayı
3
