Amniotic membrane transplantation in surgical management of ocular surface squamous neoplasias: long-term results

Basit Öğe Kaydı
dc.contributor.authorPalamar, M.
dc.contributor.authorKaya, E.
dc.contributor.authorEgrilmez, S.
dc.contributor.authorAkalin, T.
dc.contributor.authorYagci, A.
dc.date.accessioned2019-10-27T22:13:20Z
dc.date.available2019-10-27T22:13:20Z
dc.date.issued2014
dc.departmentEge Üniversitesien_US
dc.description.abstractObjective To evaluate the long-term efficacy of amniotic membrane transplantation for ocular surface reconstruction in the surgical management of ocular surface squamous neoplasia (OSSN). Methods OSSN in 21 patients (7 female, 14 male patients) was managed with excisional biopsy, cryotherapy, corneal epitheliectomy with absolute alcohol application when the cornea is involved, lamellar sclerectomy and adjunctional absolute alcohol application to the base when episclera is involved, and ocular surface reconstruction with cryopreserved amniotic membrane transplantation. Tumor control and complications were evaluated. Results The mean age of the patients was 62.42 +/- 20.9 (range, 16-84). The average diameter of the base of the tumors was 13.1 +/- 4.8 (range, 9-21) mm and complete removal was achieved in all cases as revealed histopathologically. Ocular surface healing was achieved in all cases. At the postoperative period, limbal stem cell deficiency in three eyes and mild symblepharon in one eye were detected. In a mean follow-up of 30.95 +/- 18.8 (range, 13-75) months, no recurrence was detected. Conclusion For large or multifocal conjunctival tumors, the reconstruction of ocular surface and fornix is challenging. The amniotic-membrane use to repair conjunctival defects larger than 10 mm is a safe and effective technique with minimal complications allowing surgeons to make large enough excisions.en_US
dc.identifier.doi10.1038/eye.2014.148en_US
dc.identifier.endpage1135en_US
dc.identifier.issn0950-222X
dc.identifier.issn1476-5454
dc.identifier.issue9en_US
dc.identifier.pmid24993317en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1131en_US
dc.identifier.urihttps://doi.org/10.1038/eye.2014.148
dc.identifier.urihttps://hdl.handle.net/11454/49762
dc.identifier.volume28en_US
dc.identifier.wosWOS:000342064400013en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherNature Publishing Groupen_US
dc.relation.ispartofEyeen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleAmniotic membrane transplantation in surgical management of ocular surface squamous neoplasias: long-term resultsen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu