Gastroözofageal reflü hastalar>nda yemek yeme h>z>n>n asit reflüsü ve semptomlar>na etkisi
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Tarih
2013
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Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Giriş ve Amaç: Gastroözofageal reflü ataklarının hızlı yenilen yemek sonrası arttığına inanılmakta ve hastalara yavaş yemeleri önerilmektedir. Kuvvetli bir bilimsel veriye dayandırılmasa da bu inanış temel alınarak hastalara yavaş yemek yemeleri öner- ilmektedir. Yemek yeme hızının gastroözofageal reflü hastalarında reflü ataklarına ve semptomlarına etkisini değerlendirmeyi amaçladık. Gereç ve Yöntem: Gastroözofageal reflü hastalığı semptomlu 60 hastaya (39 kadın) 24 saatlik intraözofageal pHmetri uygulandı. pH probunun yerleştirilmesinden 1 saat sonrasında hastalardan aynı öğünü (744 kkal: %37,6 karbonhidrat, %21,2 pro- tein ve %41,2 yağ) 5 veya 30 dakika içerisinde art arda 2 gün rastgele sıra ile olacak şekilde yemeleri istenmiştir. Reflü sayısı, aside maruz kalınan süre ve yemek sonrasındaki 3 saatlik süredeki semptomları analiz edilmiştir. Bulgular: Toplam 28 saatlik ölçüm periyodunda 38 hastada normal, 22 hastada patolojik intraözofageal pHmetrik ölçüm izlendi. İkinci saatte reflü sayısında artış meydana geldi. Hızlı yemek yiyen grupta 1. saatte daha az sayıda reflü atağı meydana gelirken, total reflü zamanı da daha düşüktü. Bu grupta, 2. ve 3. saatlerde bu değerlerde anlamlı olmayan bir artış gözlemlendi. Yavaş yemek yeme sonrasında semp- tom sayısı arasında (113'e 110) anlamlı bir fark gözlenmedi. Sonuç: Gastroözofageal reflü hastalarında yemek yeme hızının asidik reflü ataklarına anlamlı bir etkisi bulunmamaktadır. "Yavaş yemek yemelisin" tavsiyesi bilimsel bir temele dayanmayabilir. Bununla birlikte; kombine çok kanallı intraluminal impedans ve pH ölçümü yapılarak, non-asit ve zayıf asit reflüler değerlendirilmelidir.
Background/aims: There is a general belief that gastroesophageal reflux attacks appear more frequently after quick meal, which is without powerful scientific basis, and the general advise to patients is to eat slowly. We aimed to determine whether the speed of eating has an impact on reflux attacks and symptoms in gastroesophageal reflux disease patients. Materials and Methods: 24-h intraesophageal pH monitoring was performed to 60 patients with frequent gastroesophageal reflux disease symptoms (39 women) in a tertiary referral center. One hour after placing the pH probe, the patients were asked to have the same meal (744 kcal: 37,6% of carbohydrate, 21,2% of protein, and 41,2% of fat) within 5 or 30 minutes in random order for two consecutive days without extu- bating. the number of reflux episodes, acid exposure time, and the symptoms of 3-h postprandial period were analyzed. Results: Thirty-eight patients had normal and 22 patients had pathologic pH monitoring for a total of 28 hours of measurement period. the number of reflux episodes increased in the 2ndhour. the fast eating group had less reflux attacks and lower total reflux time in the 1sthour and an insignificant increase in the 2ndand 3rdhours. the number of symptoms was higher following slow eating (113 vs. 100) without reaching significance. Conclusion: Speed of food intake has no significant impact on acidic reflux attacks in patients with gastroesophageal reflux disease. the classical advice "eat slowly" may not have any scientific basis. However, a similar study on patients with gastroesophageal reflux disease should be performed by combined multichannel intraluminal impedance and pH to evaluate the place of nonacid or weak acid reflux.
Background/aims: There is a general belief that gastroesophageal reflux attacks appear more frequently after quick meal, which is without powerful scientific basis, and the general advise to patients is to eat slowly. We aimed to determine whether the speed of eating has an impact on reflux attacks and symptoms in gastroesophageal reflux disease patients. Materials and Methods: 24-h intraesophageal pH monitoring was performed to 60 patients with frequent gastroesophageal reflux disease symptoms (39 women) in a tertiary referral center. One hour after placing the pH probe, the patients were asked to have the same meal (744 kcal: 37,6% of carbohydrate, 21,2% of protein, and 41,2% of fat) within 5 or 30 minutes in random order for two consecutive days without extu- bating. the number of reflux episodes, acid exposure time, and the symptoms of 3-h postprandial period were analyzed. Results: Thirty-eight patients had normal and 22 patients had pathologic pH monitoring for a total of 28 hours of measurement period. the number of reflux episodes increased in the 2ndhour. the fast eating group had less reflux attacks and lower total reflux time in the 1sthour and an insignificant increase in the 2ndand 3rdhours. the number of symptoms was higher following slow eating (113 vs. 100) without reaching significance. Conclusion: Speed of food intake has no significant impact on acidic reflux attacks in patients with gastroesophageal reflux disease. the classical advice "eat slowly" may not have any scientific basis. However, a similar study on patients with gastroesophageal reflux disease should be performed by combined multichannel intraluminal impedance and pH to evaluate the place of nonacid or weak acid reflux.
Açıklama
Anahtar Kelimeler
Cerrahi
Kaynak
Turkish Journal of Gastroenterology
WoS Q Değeri
Scopus Q Değeri
Cilt
24
Sayı
5
