omega-3 Fatty Acids Have No Impact on Serum Lactate Levels After Major Gastric Cancer Surgery

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dc.contributor.authorMakay, Ozer
dc.contributor.authorKaya, Tayfun
dc.contributor.authorFirat, Ozgur
dc.contributor.authorSozbilen, Murat
dc.contributor.authorCaliskan, Cemil
dc.contributor.authorGezer, Gulten
dc.contributor.authorUyar, Mehmet
dc.contributor.authorErsin, Sinan
dc.date.accessioned2019-10-27T21:24:01Z
dc.date.available2019-10-27T21:24:01Z
dc.date.issued2011
dc.departmentEge Üniversitesien_US
dc.description30th Congress of the European-Society-for-Clinical-Nutrition-and-Metabolism (ESPEN) -- SEP 12-16, 2008 -- Florence, ITALYen_US
dc.description.abstractBackground: Preoperative and intraoperative nutrition support in patients undergoing major surgery results in decreased incidence of morbidity and mortality. Studies investigating the role of omega-3 fatty acids in these patients are increasing. Some are focused on perfusion at the cellular level. This study was undertaken to address the effect of postoperative administration of omega-3 fatty acids on cellular hypoperfusion associated with major gastric surgery. Methods: Twenty-six patients undergoing gastric cancer surgery were randomly assigned to receive parenteral nutrition (PN) supplemented with a combination of omega-6 and omega-3 fatty acids (Omegaven, 0.2 g/kg/d; Lipovenoes 10%, 0.6 g/kg/d) or with omega-6 fatty acid (Lipovenoes 10%, 0.8 g/kg/d) for 5 days. Blood samples were taken preoperatively, postoperative day 1, and on the last day of PN therapy (day 5). Results: Patients receiving omega-3 and omega-6 fatty acids showed neither lower serum lactate levels nor lower rates of complications compared with patients receiving omega-6 only. There were no statistically significant differences between the groups in other biochemical parameters, complications, or length of hospital stay or mortality. Conclusion: PN with omega-3 fatty acid supplementation does not have a significant impact on cellular hypoperfusion and lactate clearance after major gastric surgery. (JPEN J Parenter Enteral Nutr. 2011;35:488-492)en_US
dc.description.sponsorshipEuropean Soc Clin Nutr & Metabolismen_US
dc.identifier.doi10.1177/0148607110386611en_US
dc.identifier.endpage492en_US
dc.identifier.issn0148-6071
dc.identifier.issue4en_US
dc.identifier.pmid21700966en_US
dc.identifier.startpage488en_US
dc.identifier.urihttps://doi.org/10.1177/0148607110386611
dc.identifier.urihttps://hdl.handle.net/11454/44306
dc.identifier.volume35en_US
dc.identifier.wosWOS:000292051800014en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSage Publications Incen_US
dc.relation.ispartofJournal of Parenteral and Enteral Nutritionen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectomega-3 fatty acidsen_US
dc.subjectlactateen_US
dc.subjectsurgeryen_US
dc.subjectgastric canceren_US
dc.titleomega-3 Fatty Acids Have No Impact on Serum Lactate Levels After Major Gastric Cancer Surgeryen_US
dc.typeArticleen_US

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