Is it necessary to perform eye examination for patients with cutaneous atypical nevi?

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dc.contributor.authorKaraarslan, Isil
dc.contributor.authorYagci, Ayse
dc.contributor.authorAcar, Ayda
dc.contributor.authorSahin, Arzu
dc.contributor.authorOzkapu, Tugce
dc.contributor.authorPalamar, Melis
dc.contributor.authorOzdemir, Fezal
dc.date.accessioned2020-12-01T11:57:42Z
dc.date.available2020-12-01T11:57:42Z
dc.date.issued2020
dc.departmentEge Üniversitesien_US
dc.description.abstractRegular dermatological examination for patients with dysplastic nevi is indicated. However, the literature on whether those patients should also be examined by ophthalmologists or not regarding a relation between suspicious lesions for ocular melanoma and cutaneous dysplastic nevi is limited. in this study, we aimed to compare the findings of a single ophthalmologic examination between the group of patients with multiple atypical nevi with at least one histopathologically proven dysplastic nevus and another group without atypical nevi. We examined the eyes of 110 patients with multiple atypical nevi with at least one histopathologically proven dysplastic nevus (47 had the diagnosis of dysplastic nevus syndrome type A, B, C, D1 or D2) for any lesion and compared the results with a control group consisted of 110 gender, age and skin-type matched patients without atypical nevi no ocular melanoma was detected in any of the groups. the frequency of the conjunctival nevi, iris nevi, choroidal nevi and conjunctival acquired melanosis were similar in both groups. Iris freckles were detected more frequently in the study group. Conjunctival racial hyperpigmentation was detected more frequently in the control group (P < .05). in this study, any significant difference in the distribution of the ocular lesions with any risk of malignancy in the study and control groups was not observed. However, considering the limitations of the study, there may still be a need of regular ophthalmic examination for the patients with atypical nevi in case of having high risk factors for developing melanoma.en_US
dc.identifier.doi10.1111/dth.14503en_US
dc.identifier.issn1396-0296
dc.identifier.issn1529-8019
dc.identifier.pmid33142003en_US
dc.identifier.urihttps://doi.org/10.1111/dth.14503
dc.identifier.urihttps://hdl.handle.net/11454/61774
dc.identifier.wosWOS:000587897800001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofDermatologic Therapyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectdysplastic nevusen_US
dc.subjectocular melanomaen_US
dc.subjectophthalmic examinationen_US
dc.titleIs it necessary to perform eye examination for patients with cutaneous atypical nevi?en_US
dc.typeArticleen_US

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