Does casein phosphopeptid amorphous calcium phosphate provide remineralization on white spot lesions and inhibition of Streptococcus mutans?

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dc.contributor.authorAykut-Yetkiner A.
dc.contributor.authorKara N.
dc.contributor.authorAteş M.
dc.contributor.authorErsin N.
dc.contributor.authorErtuğrul F.
dc.date.accessioned2019-10-26T21:27:42Z
dc.date.available2019-10-26T21:27:42Z
dc.date.issued2014
dc.departmentEge Üniversitesien_US
dc.description.abstractOBJECTIVE: The aim of this study was to evaluate the remineralization effect of Casein Phosphopeptid Amorphous Calcium Phosphate (CPP-ACP) on white spot lesions (WSL) and its inhibitory effect on Streptococcus mutans colonization.STUDY DESIGN: The study group consisted of 60 children exhibiting at least 1-WSL. Subjects were randomly divided into 2 groups: a test group of using CPP-ACP cream (Tooth Mousse, GC Europe N.V., Leuven, Belgium) and a control group using only fluoride containing toothpaste for a period of 3-months. Baseline WSLs were scored using DIAGNOdent device (KaVo Germany) and the saliva samples were collected to measure S. mutans counts. After the 3-month period the WSLs were again recorded and the saliva sample collection was repeated. Wilcoxon Signed Ranks Test was used for statistical analysis.RESULTS: DIAGNOdent measurements were increased by time (p = 0.002) in control group and no statistically significant diference (p = 0.217) was found in test group by the 3-month period. In both groups, the mutans counts were decreased in 3-month experimental period.CONCLUSIONS: These clinical and laboratory results suggested that CPP-ACP containing cream had a slight remineralization effect on the WSL in the 3-month evaluation period however longer observation is recommended to confirm whether the greater change in WSLs is maintained.en_US
dc.identifier.doi10.17796/jcpd.38.4.b4q401v6m4818215en_US
dc.identifier.endpage306en_US
dc.identifier.issn1053-4628
dc.identifier.issue4en_US
dc.identifier.pmid25571679en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage302en_US
dc.identifier.urihttps://doi.org/10.17796/jcpd.38.4.b4q401v6m4818215
dc.identifier.urihttps://hdl.handle.net/11454/17431
dc.identifier.volume38en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofThe Journal of clinical pediatric dentistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleDoes casein phosphopeptid amorphous calcium phosphate provide remineralization on white spot lesions and inhibition of Streptococcus mutans?en_US
dc.typeArticleen_US

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