Validity of proposed DSM-5 ADHD impulsivity symptoms in children

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dc.contributor.authorBolat, Gul Unsel
dc.contributor.authorErcan, Eyup Sabri
dc.contributor.authorSalum, Giovanni Abrahao
dc.contributor.authorBilac, Oznur
dc.contributor.authorMassuti, Rafael
dc.contributor.authorOzaslan, Taciser Uysal
dc.contributor.authorBolat, Hilmi
dc.contributor.authorRohde, Luis Augusto
dc.date.accessioned2019-10-27T11:25:58Z
dc.date.available2019-10-27T11:25:58Z
dc.date.issued2016
dc.departmentEge Üniversitesien_US
dc.description.abstractThe American Psychiatric Association (APA) working group on Attention-Deficit/Hyperactivity Disorder (ADHD) proposed the inclusion of four new impulsivity symptoms. However, they were not included in DSM-5 due to the lack of sufficient evidence. The aim of this study is to investigate the performance of the proposed four ADHD impulsivity symptoms with respect to: (a) ADHD factor structure; (b) performance in predicting clinical impairment; (c) specificity for ADHD diagnosis and (d) best symptomatic threshold to predict clinical impairment. The sample comprised 416 children (31 ADHD subjects according to both DSM-IV and proposed DSM-5, 20 ADHD subjects according to just one diagnostic system and 365 controls) from 12 schools. Diagnoses were derived using semi-structured interviews and ADHD rating scales. Results from confirmatory factor analysis indicate that addition of the four new impulsivity items provided a slightly better factor structure if compared to models including only 18 items. Regression analyses showed that only one of the new impulsivity symptoms (impatient) was part of the list of best predictors of impairment. None of the four new impulsivity items was specifically associated with ADHD diagnosis. The best cutoff point in the hyperactivity/impulsivity dimension for predicting impairment did not change significantly. Overall, our findings suggest that the determination on how to best capture impulsivity dimension as part of the ADHD construct needs more investigation and that there is not enough evidence to include these four assessed impulsivity symptoms as part of the ADHD criteria.en_US
dc.description.sponsorshipShire; Eli-LillyEli Lilly; Janssen-CilagJohnson & Johnson USAJanssen Biotech Inc; NovartisNovartisen_US
dc.description.sponsorshipLuis A. Rohde has received honoraria, has been on the speakers' bureau/advisory board and/or has acted as a consultant for Eli-Lilly, Janssen-Cilag, Novartis and Shire in the last 3 years. He receives authorship royalties from Oxford Press and ArtMed. He also received travel awards for taking part of 2014 APA and 2015 WFADHD meetings from Shire. The ADHD and Juvenile Bipolar Disorder Outpatient Programs chaired by him received unrestricted educational and research support from the following pharmaceutical companies in the last 3 years: Eli-Lilly, Janssen-Cilag, Novartis, and Shire. Eyup Sabri Ercan is in charge of the advisory board of Lilly and Janssen-Cilag. The other authors have no biomedical financial interests or potential conflicts of interest to report.en_US
dc.identifier.doi10.1007/s00787-016-0839-0en_US
dc.identifier.endpage1132en_US
dc.identifier.issn1018-8827
dc.identifier.issn1435-165X
dc.identifier.issue10en_US
dc.identifier.pmid26979524en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1121en_US
dc.identifier.urihttps://doi.org/10.1007/s00787-016-0839-0
dc.identifier.urihttps://hdl.handle.net/11454/33446
dc.identifier.volume25en_US
dc.identifier.wosWOS:000385059900009en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofEuropean Child & Adolescent Psychiatryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDSM-5en_US
dc.subjectADHDen_US
dc.subjectConfirmatory factor analysisen_US
dc.subjectImpulsivityen_US
dc.titleValidity of proposed DSM-5 ADHD impulsivity symptoms in childrenen_US
dc.typeArticleen_US

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